Can I take Atorvastatin and Milk thistle extract together?

Perché succede

Milk thistle contains a compound called silymarin. Silymarin can interfere with certain proteins (transporters) and enzymes in the liver that are responsible for breaking down and removing atorvastatin from your body. If the liver cannot process the statin as quickly as usual, the drug levels can rise.

Use caution if combining these two. If you decide to take milk thistle, monitor yourself closely for any new or unusual muscle pain, tenderness, or weakness, as well as any yellowing of the skin or eyes (jaundice). It is best to inform your doctor or pharmacist before starting milk thistle so they can ensure your statin dose remains appropriate for you.

Gravidanza

Non devi assumere atorvastatina se sei incinta o stai pianificando di diventare incinta, poiché può causare gravi danni a un bambino non ancora nato. Usa un contraccettivo efficace mentre prendi questo medicinale.

Muscle disorders - atorvastatin

You must report any unexplained muscle pain, tenderness, or weakness to your doctor immediately, as this can rarely lead to serious kidney damage.

Hormone-sensitive conditions (e.g. breast cancer, endometriosis)

Avoid milk thistle if you have a history of hormone-sensitive cancers or conditions, as it may have oestrogen-like effects that could worsen these conditions.

Succo di pompelmo

Grapefruit juice contains compounds that can increase the level of atorvastatin in your blood. This can increase your risk of side effects, such as muscle pain or liver problems. You should avoid drinking large quantities (more than 1.2 litres daily), but it is safest to avoid it altogether while taking this medicine.

Alcol

While alcohol does not directly interact with atorvastatin, drinking large amounts of alcohol can increase the risk of liver damage and may raise triglyceride levels, which can counteract the benefits of the medicine. It is advised to keep alcohol intake within recommended limits.

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Avvertenza

Queste informazioni sono solo a scopo educativo generale e non devono essere considerate un sostituto del consiglio medico professionale. Consultate sempre il vostro medico di base, farmacista o un altro professionista sanitario qualificato prima di prendere decisioni sui vostri farmaci. Le circostanze individuali possono variare, e solo un professionista sanitario che conosce la vostra storia medica può fornire una guida personalizzata.