Can I take Apixaban and Empagliflozin together?

Perché succede

Apixaban (a blood thinner) and empagliflozin (a diabetes medication) are processed by different pathways in the body. Apixaban is mainly broken down by specific liver enzymes (CYP3A4) and a transport protein (P-gp), while empagliflozin is processed through a different liver pathway (glucuronidation) and removed by the kidneys. They do not interfere with how each other works or how they are cleared from the system.

You can continue taking both medications as prescribed by your doctor. However, because empagliflozin can have a mild diuretic effect (making you pass more urine), ensure you stay well-hydrated. Always inform your healthcare provider if you notice any unusual bruising or bleeding, which is a general precaution when taking any blood thinner like apixaban.

Chirurgia o procedure dentali

You must tell your surgeon or dentist you are taking apixaban before any procedure, as it significantly increases your risk of bleeding and may need to be stopped temporarily.

Diabetic Ketoacidosis (DKA)

Empagliflozin can cause a serious condition called ketoacidosis even if your blood sugar levels are near normal. Seek urgent medical help if you experience nausea, vomiting, or stomach pain.

Fournier's gangrene - empagliflozin

Seek immediate medical attention if you experience pain, tenderness, redness, or swelling in the genital or anal area, accompanied by fever or malaise.

Alcol

While there is no direct chemical interaction, you should be cautious. For apixaban, heavy drinking increases the risk of stomach bleeding. For empagliflozin, alcohol can increase the risk of dehydration, low blood sugar (hypoglycaemia), and a serious condition called ketoacidosis. Stick to moderate amounts.

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Avvertenza

Queste informazioni sono solo a scopo educativo generale e non devono essere considerate un sostituto del consiglio medico professionale. Consultate sempre il vostro medico di base, farmacista o un altro professionista sanitario qualificato prima di prendere decisioni sui vostri farmaci. Le circostanze individuali possono variare, e solo un professionista sanitario che conosce la vostra storia medica può fornire una guida personalizzata.