Can I take Apixaban and Atorvastatin together?

Perché succede

Apixaban and atorvastatin are processed by the same enzyme in the liver (CYP3A4). However, atorvastatin is not a strong enough inhibitor or inducer of this enzyme to change the levels of apixaban in your blood to a degree that would cause concern.

You can continue taking both medications as prescribed by your doctor. You do not need to change your routine or dose. As with any blood thinner, you should always watch for signs of unusual bleeding or bruising and report them to your healthcare provider.

Bleeding risk - apixaban

You must seek immediate medical attention if you experience a serious fall or head injury, even if you feel fine, as you are at high risk of internal bleeding. Always inform healthcare professionals, including dentists, that you are taking an anticoagulant before any procedure.

Gravidanza

Non assumere atorvastatin if you are pregnant or planning to become pregnant, as it can cause serious harm to an unborn baby. You must use effective contraception while taking it.

Muscle damage - atorvastatin

You must report any unexplained muscle pain, tenderness, or weakness to your doctor immediately, as this can rarely lead to serious kidney problems.

Succo di pompelmo

Grapefruit juice can increase the level of atorvastatin in your blood, which may increase the risk of side effects like muscle pain. Avoid drinking large quantities (more than 1.2 litres per day), though a small glass is usually fine.

Alcol

While there is no direct interaction, drinking large amounts of alcohol can increase the risk of liver problems with atorvastatin and increase the risk of stomach bleeding while taking apixaban. It is best to keep to moderate limits.

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Avvertenza

Queste informazioni sono solo a scopo educativo generale e non devono essere considerate un sostituto del consiglio medico professionale. Consultate sempre il vostro medico di base, farmacista o un altro professionista sanitario qualificato prima di prendere decisioni sui vostri farmaci. Le circostanze individuali possono variare, e solo un professionista sanitario che conosce la vostra storia medica può fornire una guida personalizzata.