Posso prendere Lercanidipina e Pregabalin insieme?

Perché succede

Lercanidipine works by relaxing blood vessels, which can sometimes cause fluid to leak into the tissues (swelling). Pregabalin affects the central nervous system and can also cause fluid retention and drowsiness. When used together, their similar side-effect profiles can have an additive effect on your body.

Cosa dovresti fare

It is generally safe to take these together, but you should be aware of increased side effects. To stay safe, get up slowly from a sitting or lying position to avoid dizziness. If you notice significant swelling in your ankles, or if the drowsiness interferes with your daily activities (like driving), speak to your GP. Do not stop taking either medication without medical advice.

Precauzioni importanti

Disturbi della salute mentale

Il pregabalin può causare pensieri suicidi o l'impulso di autolesionismo. Devi cercare immediatamente assistenza medica se il tuo umore cambia o hai pensieri di farti del male.

Gravidanza

Pregabalin must not be used during pregnancy unless specifically advised by a specialist, as it may increase the risk of birth defects. Effective contraception must be used during treatment.

Severe respiratory issues or opioid use

Pregabalin can cause serious, life-threatening breathing problems, especially if you already have lung disease or if you take it alongside opioid painkillers or other sedatives.

History of drug or alcohol misuse

Pregabalin carries a high risk of dependence and addiction. It is a controlled drug because it can be misused, particularly if you have a history of substance abuse.

Severe liver or kidney disease

Lercanidipine is not recommended if you have severe liver or kidney problems. Ensure your doctor is aware of your condition before starting treatment.

Avvertenze su cibo e bevande

Alcol

It is best to avoid or strictly limit alcohol while taking these medicines. For lercanidipine, alcohol can increase the blood-pressure-lowering effect, making you feel dizzy or faint. For pregabalin, alcohol increases the risk of severe drowsiness, dizziness, and breathing problems. Combining alcohol with these medicines increases the risk of accidents and liver strain.

Pompelmo e succo di pompelmo

You must not eat grapefruit or drink grapefruit juice while taking lercanidipine. Grapefruit can significantly increase the amount of the medicine in your blood, making side effects like dizziness, headaches, and a fast heartbeat much more likely.

Pasti ricchi di grassi

Lercanidipine should be taken at least 15 minutes before a meal. Taking it with or immediately after a high-fat meal can significantly increase the amount of medicine absorbed by your body, which may lead to more side effects.

Uso di altri medicinali

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Avvertenza

Queste informazioni sono solo a scopo educativo generale e non devono essere considerate un sostituto del consiglio medico professionale. Consultate sempre il vostro medico di base, farmacista o un altro professionista sanitario qualificato prima di prendere decisioni sui vostri farmaci. Le circostanze individuali possono variare, e solo un professionista sanitario che conosce la vostra storia medica può fornire una guida personalizzata.