Posso prendere Evolocumab e Furosemide insieme?

Perché succede

Evolocumab is a monoclonal antibody that helps the liver remove cholesterol from the blood. Furosemide is a diuretic (water tablet) that helps the kidneys remove excess salt and water. These medicines are processed by different pathways in the body and do not overlap in their actions.

You can safely take these two medicines together as prescribed by your doctor. No special precautions or dose changes are needed. Always inform your healthcare provider of all medications you are taking, including over-the-counter supplements.

Dehydration and low blood pressure

Furosemide is a potent diuretic. You must not take it if you are already severely dehydrated or cannot pass urine. It can cause a rapid drop in blood pressure and salt levels, especially if you are also taking other blood pressure medicines.

Gotta

La furosemide può aumentare i livelli di acido urico nel sangue, il che potrebbe scatenare un attacco di gotta doloroso o peggiorare la gotta già presente.

Latex allergy - evolocumab

The needle cover of the pre-filled syringe/pen contains dry natural rubber (a derivative of latex), which may cause severe allergic reactions in people with a sensitive latex allergy.

Alcol

It is best to avoid or strictly limit alcohol while taking furosemide. Both alcohol and furosemide can lower your blood pressure and have a diuretic effect (making you pee more). Combining them increases the risk of dizziness, lightheadedness, or fainting, especially when standing up. It can also lead to dehydration.

It is best to avoid or strictly limit alcohol while taking evolocumab. Combining alcohol with cholesterol-lowering treatments can increase the risk of liver strain or damage.

Liquorice (Natural) / Liquorice Root

Avoid eating large amounts of natural liquorice or taking liquorice root supplements. Natural liquorice can cause the body to lose potassium and retain salt, which opposes the action of furosemide and can lead to dangerously low potassium levels.

Caffeina (Caffè, Tè, Bevande Energetiche)

Limit your intake of caffeine. Caffeine is a mild diuretic and can increase the water-loss effect of furosemide, potentially increasing the risk of dehydration or electrolyte imbalances.

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Avvertenza

Queste informazioni sono solo a scopo educativo generale e non devono essere considerate un sostituto del consiglio medico professionale. Consultate sempre il vostro medico di base, farmacista o un altro professionista sanitario qualificato prima di prendere decisioni sui vostri farmaci. Le circostanze individuali possono variare, e solo un professionista sanitario che conosce la vostra storia medica può fornire una guida personalizzata.