Can I take Citalopram and Co-codamol together?

Perché succede

Both drugs affect a chemical in the brain called serotonin; when levels get too high, it causes side effects. Citalopram can also block the liver enzyme (CYP2D6) needed to convert codeine into its active form (morphine), potentially making the painkiller less effective. Both drugs also have 'depressant' effects on the central nervous system, which increases sleepiness.

You can take these together if your doctor has prescribed them, but you should be aware of the signs of serotonin syndrome (such as shivering, diarrhoea, confusion, muscle stiffness, or a high temperature). If you feel very drowsy or find the co-codamol isn't helping your pain, speak to your GP. Avoid alcohol while taking these medicines.

Sindrome serotoninergica

Taking these medicines together increases the risk of serotonin syndrome, a potentially life-threatening condition. Seek immediate medical help if you experience agitation, hallucinations, fast heartbeat, or severe muscle stiffness.

Heart rhythm disorders (Long QT syndrome)

Citalopram can affect your heart rhythm. You must not take it if you have a pre-existing heart rhythm problem or are taking other medicines that affect the heart's electrical activity.

Bassi livelli di sodio (Iponatriemia)

Citalopram can cause a serious drop in blood sodium levels, especially in the elderly. Seek medical help if you experience extreme tiredness, confusion, or muscle twitching.

Breathing problems (e.g. asthma, COPD)

The codeine in co-codamol can dangerously slow down your breathing. Do not take this if you have severe lung disease or are having an asthma attack.

Addiction and dependency

Co-codamol contains an opioid which can be highly addictive. Do not use it for more than 3 days at a time without medical supervision, as this can lead to withdrawal symptoms and 'medication-overuse' headaches.

Alcol

You should avoid or strictly limit alcohol while taking these medicines. Both citalopram and the codeine in co-codamol can cause drowsiness and dizziness. Alcohol significantly increases these effects, making you feel much sleepier and increasing the risk of falls or accidents. In the case of co-codamol, alcohol also increases the risk of dangerous breathing problems.

Caffeine (Coffee, tea, energy drinks)

Be cautious with high amounts of caffeine. Some versions of co-codamol already contain caffeine as an extra ingredient. Adding more caffeine from drinks can make you feel shaky, anxious, or cause a racing heart.

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Avvertenza

Queste informazioni sono solo a scopo educativo generale e non devono essere considerate un sostituto del consiglio medico professionale. Consultate sempre il vostro medico di base, farmacista o un altro professionista sanitario qualificato prima di prendere decisioni sui vostri farmaci. Le circostanze individuali possono variare, e solo un professionista sanitario che conosce la vostra storia medica può fornire una guida personalizzata.