Can I take Bactrim and Gly-coramin together?

Why this happens

Bactrim (co-trimoxazole) can sometimes increase the effect of certain medications or natural processes that lower blood sugar. Gly-Coramin contains glucose, but it also contains nikethamide, a stimulant. In some cases, the sulfonamide component of Bactrim can interfere with how the body handles blood sugar, potentially leading to unexpected drops.

What you should do

Use this combination with caution. If you have diabetes or problems with blood sugar, monitor your levels more frequently. Watch out for signs of low blood sugar, such as feeling shaky, sweaty, dizzy, or confused. If you feel unwell, contact your doctor or pharmacist.

Important precautions

Severe Skin Reactions

Stop taking Bactrim immediately and seek urgent medical help if you develop a skin rash, peeling, or mouth sores. These can be signs of rare but life-threatening skin reactions (Stevens-Johnson syndrome or toxic epidermal necrolysis).

Pregnancy (Third Trimester)

Do not take Bactrim if you are in the final weeks of pregnancy. It can cause a serious type of jaundice (kernicterus) in the newborn baby by displacing bilirubin in the blood.

Doping in Sport

Gly-Coramin contains nikethamide, which is a prohibited substance in competitive sports. It will result in a positive drug test during or out of competition.

Food and drink warnings

Alcohol

While rare, some people experience a 'disulfiram-like reaction' when mixing Bactrim with alcohol. This can cause flushing, nausea, palpitations, and breathlessness. It is best to avoid alcohol during treatment and for 48 hours after finishing the course.

Caffeine

Gly-Coramin contains a stimulant. Consuming high amounts of caffeine (found in coffee, tea, energy drinks, and chocolate) may increase the risk of side effects such as restlessness, racing heart, and tremors.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.