Can I take Atorvastatin and White button together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
- Add to preferred sources on Google
There is no known interaction between atorvastatin and white button mushrooms (Agaricus bisporus). In fact, some studies suggest that white button mushrooms may have a beneficial effect on cholesterol levels, though they are not a replacement for your prescribed medication.
Why this happens
White button mushrooms do not affect the liver enzymes (specifically CYP3A4) that break down atorvastatin, nor do they interfere with how the drug is absorbed or excreted by the body.
What you should do
You can safely eat white button mushrooms while taking atorvastatin. Continue to take your medication as prescribed by your doctor. If you are considering taking concentrated mushroom supplements or powders, it is always best to check with your pharmacist first, as these are much stronger than culinary mushrooms.
Important precautions
Pregnancy
You must not take atorvastatin if you are pregnant or planning to become pregnant, as it can cause serious harm to an unborn baby. Use effective contraception while taking this medicine.
Muscle disorders - atorvastatin
Seek immediate medical advice if you experience unexplained muscle pain, tenderness, or weakness. In rare cases, this can lead to a serious condition called rhabdomyolysis which causes kidney damage.
Food and drink warnings
Grapefruit juice
Grapefruit juice contains compounds that can increase the level of atorvastatin in your blood. This may increase your risk of side effects, such as muscle pain or damage. Avoid drinking large quantities (more than 1.2 litres per day), though it is safest to avoid it altogether or keep intake to very small amounts.
Alcohol
While alcohol does not directly interact with atorvastatin, drinking large amounts of alcohol can increase the risk of liver problems and muscle side effects. It is best to keep your intake within the recommended limits (no more than 14 units per week).
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Drug interactions checker
Can I take Sertraline and Fluoxetine together?
Taking sertraline and fluoxetine together significantly increases the risk of a rare but serious condition called serotonin syndrome. This happens because both medicines work by increasing the level of a chemical called serotonin in your brain. If levels get too high, it can cause symptoms like shivering, diarrhoea, confusion, severe muscle tightness, fever, and even seizures. Additionally, fluoxetine can slow down how your body breaks down sertraline, leading to a build-up of the drug in your system and increasing the risk of side effects.

Drug interactions checker
Can I take Naproxen and Tramadol together?
Taking naproxen and tramadol together can increase the risk of serious side effects, particularly affecting your stomach and kidneys. There is also a small but important risk of seizures (fits) and a rare condition called serotonin syndrome. However, these two medicines are often prescribed together for short-term pain relief under medical supervision.
Article history
The information on this page is written and peer reviewed by qualified clinicians.
Article also available in English, German, Spanish, French, Italian, Portuguese, Hindi, Hebrew, Arabic, and Swedish.
25 Jan 2026 | Originally published
Join the conversation
Share your thoughts or experiences with others in our patient communities.

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.
More in drug interactions checker
- Can I take Alogliptin and Rybelsus together?
- Can I take Amlodipine and Apixaban together?
- Can I take Amlodipine and Nustendi together?
- Can I take antihistamines while pregnant?
- Can I take antihistamines with alcohol?
- Can I take Atorvastatin and Tamsulosin together?
- Can I take Bactrim and Venlafaxine together?
- Can I take Clopidogrel and Paracetamol together?
- Can I take Cordyceps and Shiitake together?
- Can I take Esomeprazole and Fexofenadine together?
- Can I take Esomeprazole and Vitamin C together?
- Can I take Furosemide and Strivit D3 together?
- Can I take Gabapentin and Naproxen together?
- Can I take Indapamide and Magnesium together?
- Can I take Levothyroxine and Vitamin B12 together?
- Can I take Maitake and Royal sun together?
- Can I take Metformin and Sertraline together?
- Can I take Mirtazapine and Paracetamol together?
- Can I take Naproxen and Ropinirole together?
- Can I take Sedoxil and Wellbutrin together?