Can I take Apixaban and Naproxen together?

Perché succede

Apixaban is an anticoagulant (blood thinner) that prevents clots by blocking a specific clotting factor. Naproxen is a non-steroidal anti-inflammatory drug (NSAID) that also thins the blood by preventing platelets from sticking together. Additionally, naproxen can irritate the lining of the stomach. When used together, their blood-thinning effects add up, making it much harder for your body to stop any bleeding that starts.

You should avoid taking naproxen while you are on apixaban unless your doctor has specifically told you to do so and is monitoring you closely. If you need pain relief, paracetamol is generally a safer alternative. If you have already taken both and notice any unusual bleeding, severe headache, or dark stools, seek medical attention immediately.

Combined use (Drug-Drug Interaction)

Do not take naproxen while taking apixaban unless specifically directed by a specialist. Taking both significantly increases your risk of life-threatening internal bleeding. Use paracetamol for pain relief instead.

Asma

Do not take naproxen if you have ever had wheezing, runny nose, or a skin rash after taking aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs), as it can trigger a severe or fatal asthma attack.

Stomach Ulcers

Avoid naproxen if you have a history of stomach ulcers or intestinal bleeding, as it can cause new bleeding or perforation of the stomach lining, which may be fatal.

Alcol

You should limit or avoid alcohol while taking these medicines. Both apixaban and naproxen increase your risk of bleeding in the stomach and intestines; drinking alcohol further irritates the stomach lining and can significantly increase this risk.

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Avvertenza

Queste informazioni sono solo a scopo educativo generale e non devono essere considerate un sostituto del consiglio medico professionale. Consultate sempre il vostro medico di base, farmacista o un altro professionista sanitario qualificato prima di prendere decisioni sui vostri farmaci. Le circostanze individuali possono variare, e solo un professionista sanitario che conosce la vostra storia medica può fornire una guida personalizzata.