A Study of Clinical and Immune Responses to Sequential Biologic Therapies in Psoriatic Arthritis

To take part in this study, you need to be an adult (aged 18 or older) who has been diagnosed with psoriatic arthritis. You also need to be starting a new advanced medication, like a biologic or targeted synthetic DMARD, as part of your usual treatment plan. It doesn't matter if this is your first time trying such a medication or if you've tried others before.

However, you wouldn't be able to join if you're only switching your medication for psoriasis (skin condition) or a back problem called spondyloarthritis, without also having active psoriatic arthritis. Also, if you're going back on a medication you've used before, you wouldn't be eligible. Lastly, if you are unable or unwilling to give your full permission to take part, you cannot join.

If you choose to join this study, you would give your permission for researchers to collect information about your health. This involves allowing them to use information from your routine NHS clinic visits for psoriatic arthritis, which typically last about 52 weeks (one year). During these visits, your doctor will check your symptoms and how well your treatment is working, just like usual.

You would also be asked to fill in some questionnaires about your symptoms and how your condition affects your daily life. Additionally, you'd need to provide a few extra blood samples for research purposes. These will be taken at the start of the study and then again around 12 weeks later, often at the same time as your routine blood tests. There are no extra medications provided by the study; you'll receive your treatment as prescribed by your own doctor.