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Ovarian Cancer Radiomics Approach in CT Led Evaluation

This study, called "Ovarian Cancer Radiomics Approach in CT Led Evaluation," is looking into a new way to understand ovarian cancer using advanced computer analysis of standard CT scans. Currently, all patients with suspected or confirmed ovarian cancer have a CT scan before treatment to help guide surgery and chemotherapy. This new method, called radiomics, looks for tiny details in these scans that aren't visible to the human eye. Researchers at Imperial College London want to find out if this detailed information can help create more tailored treatment plans for each patient. They also hope to learn how different types of ovarian cancer relate to these scan findings, which could lead to better treatments in the future.

A colpo d'occhio

Stato
Reclutamento
Sponsor
Imperial College Healthcare NHS Trust
Obiettivo di iscrizione
168
Inizio
10 Feb 2025
Completamento stimato
01 Jan 2032

Di cosa tratta questo studio?

When someone is thought to have ovarian cancer, or it's confirmed, doctors usually plan treatment that involves surgery and chemotherapy. Even with the best care, it can be tricky to know exactly how well a person will respond to these treatments beforehand. To help guide this, everyone has a CT scan before treatment. This scan helps doctors see where the cancer is.

Now, there's a new approach called 'radiomics'. This involves using clever computer programs to look very closely at these routine CT scans. These computers can spot tiny patterns and features in the scan pictures that an eye can't pick up. We believe this could give us much more detailed information about the ovarian cancer.

The main goal of this particular study is to see if this new, detailed scan information can help doctors choose the very best treatment plan that is just right for each individual patient. This means making treatment as effective as possible for you. We also want to understand if different kinds of ovarian cancer show up differently with this radiomics method, which could help in developing new and better treatments for the future.

Punti chiave

  • This study uses advanced computer analysis of your routine CT scans.
  • It aims to find hidden details in scans to understand ovarian cancer better.
  • The goal is to develop more personalised treatment plans for future patients.
  • No extra tests or appointments are needed from you.
  • Your medical care will not be affected by participating.
  • Your scan information will be kept anonymous.

Chi può essere idoneo?

To be part of this study, you need to be at least 18 years old and have suspected or confirmed advanced ovarian cancer. This means your cancer is at a stage where it's spread a bit but you're still able to have active treatments like surgery followed by chemotherapy, or chemotherapy first then surgery. You'll also need to have had a standard CT scan before your treatment where your cancer is clearly visible and large enough to be seen – at least 2cm.

There are some reasons why you might not be able to join. For example, if you're pregnant, or if you have a known allergy to the dye used in CT scans, or kidney problems that mean you can't have the dye. If you're only having comfort care (palliative care) at the start, or if previous surgery removed an ovarian growth, you wouldn't be able to join. Also, if the CT scan images aren't clear enough, perhaps due to metal in your body, you might not be suitable.

Questo studio potrebbe fare al caso tuo?

Rispondi a queste domande rapide per vedere se potresti essere idoneo. Questo è solo una guida — il team di ricerca prende la decisione finale.

  1. Hai 18 anni o più?
  2. Do you have suspected or confirmed advanced ovarian cancer?
  3. Are you having surgery and/or chemotherapy as a main treatment plan?
  4. Have you had a CT scan before treatment where your cancer was visible (at least 2cm)?
  5. Are you able to provide written consent to take part?
  6. Non sei attualmente incinta?
Rispondi a ogni domanda per vedere il tuo risultato.

Cosa comporta la partecipazione?

This study doesn't involve any extra appointments, medications, or tests for you. It uses information from your routine CT scans that you would have anyway as part of your standard care for ovarian cancer. Researchers will take anonymised data from these scans and use their special computer methods to analyse them. You won't need to do anything different from what your doctors have already planned for your treatment. There's no additional time commitment beyond your usual medical appointments.

Rischi e benefici potenziali

Since this study only uses information from CT scans you would have anyway, there are no direct extra risks to you. There are also no direct benefits to you personally from taking part, as it's a research study looking at new ways to understand scans. However, the information gathered from your scans could help future patients with ovarian cancer by leading to more personalised treatment plans and a better understanding of the disease. You are free to decide not to take part or to withdraw your permission for your anonymous scan data to be used at any time, without affecting your medical care.

Luoghi (1)

  • Imperial College NHS Healthcare Trust
    Codice postale verificato
    Londra, Regno Unito· Reclutamento

Domande comuni

What is 'radiomics'?

Radiomics is a new computer method that analyses detailed patterns in medical scans like CTs, spotting things the human eye can't, to give more information about conditions like cancer.

Do I need extra scans or tests for this study?

No, you don't need any extra scans or tests. The study uses information from the CT scans you would have as part of your normal ovarian cancer care.

Will taking part change my treatment?

No, this study will not change your current treatment plan. It's about gathering information to help improve treatment for future patients.

Chi sta conducendo questo studio?

This research is being conducted by a group at Imperial College London, who have developed these new computer analysis methods.

What happens to my scan information?

Your scan information will be made anonymous so it can't be linked back to you personally. It will then be analysed by special computer programs for research purposes.

Come saperne di più

Christina Fotopoulou, MD, PhD

Parla sempre con il tuo medico di base o specialista prima di decidere di partecipare a uno studio.

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