A Research Study to Evaluate the Efficacy and Safety of Cenerimod in Subjects Suffering From Systemic Lupus Erythematosus

To join this study, you need to be an adult between 18 and 75 years old and have had a diagnosis of Systemic Lupus Erythematosus (SLE) for at least six months. Your lupus symptoms should be active and moderately severe, as judged by specific medical scores.

You also need to be taking certain medicines for your lupus already. These could include anti-malarials (like hydroxychloroquine), mycophenolate mofetil or mycophenolic acid, azathioprine, methotrexate, specific steroid doses (like prednisone), or belimumab. The timing of when you started these medicines is also important.

For women who could become pregnant, you would need to have a negative pregnancy test and agree to use reliable contraception throughout the study and for six months afterwards. The study team will check all these details carefully to make sure it's the right fit for you.

If you join this study, you will be in it for about 12 months. Throughout this time, you'll continue taking your usual lupus medicines. In addition, you'll either receive the study medicine, cenerimod, or a placebo (a dummy pill that looks like the active medicine but contains no active drug). You won't know which one you're receiving, and neither will your study doctor, to ensure fair results. You'll need to attend regular clinic visits for check-ups, assessments of your lupus symptoms, and to have blood or urine tests. These visits help the research team keep track of your health, how your lupus is doing, and if the study medicine is having any effects.