Impact of Forced Diuresis on the Residual Fragment Rate After Flexible Ureteroscopy for Destruction of Kidney Stones With Laser

To be part of this study, you need to be an adult between 18 and 80 years old, and you must be scheduled to have laser surgery (flexible ureteroscopy) to break up kidney stones. You also need to be covered by the UK social security system (like NHS services) and be able to understand and sign a consent form, showing you agree to take part. It's important that you can follow the study's instructions.

There are certain reasons why you wouldn't be able to join. This includes if you are pregnant, breastfeeding, under 18, or if a court decision means you can't make your own choices. You also can't participate if you have any serious health conditions that would make Furosemide unsafe for you. This includes severe kidney problems, very low potassium or sodium levels, severe dehydration, or serious liver disease. If you're already taking Furosemide regularly, or if you need certain other strong antibiotics (like Aminoside or Vancomycin) around the time of your procedure, you won't be able to join. Finally, if you're already in another study testing a new medicine or medical device, you wouldn't be eligible for this one.

If you decide to take part in this study, you will be given a water tablet called Furosemide through an injection, along with extra fluids given into your vein (like a drip), after your kidney stone laser surgery. The doctors will then monitor you as part of your standard care. The main focus of the study is observing how well your body clears the tiny stone fragments. There will likely be follow-up appointments and scans to check if any fragments remain in your kidney. The total duration of your involvement in the study would depend on how long these checks are needed to see the full effect of the treatment.