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Triamterene - una compressa 'acqua' o diuretico

Dyrenium

Nota dell'autore clinico Michael Stewart 15/06/2022: Triamterene capsules were discontinued in the UK in November 2021. Currently triamterene is only available in the UK in combination with another diuretic medicine called clortalidone. At the time of review there are no branded or generic products solely containing triamterene available in the UK. Products may still be available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.

Triamterene is a 'water' tablet (diuretic) - it will make you want to go to the toilet more often to pass urine.

It may cause your urine to look slightly blue in some lights - this is harmless.

Eventuali effetti collaterali sono generalmente lievi.


A colpo d'occhio

  • Triamterene is a potassium-sparing diuretic used to treat water retention (oedema).

  • It helps prevent fluid build-up by increasing urine production.

  • In the UK, it is only available in combination with chlortalidone.

  • Take triamterene as prescribed, usually with breakfast and at lunchtime.

  • Avoid 'salt substitutes' as triamterene can increase potassium levels in your body.

  • Your doctor will monitor your blood salt levels with regular blood tests.

  • Seek medical advice if you experience persistent side-effects like feeling sick or diarrhoea.

About triamterene

Tipo di medicinale

A potassium-sparing diuretic

Utilizzato per

Water retention (oedema)

Chiamato anche

Dyrenium® (USA);
Combinations: Triamterene with clortalidone, triamterene with hydrochlorothiazide

Disponibile come

Triamterene 50 mg/ chlortalidone 50 mg tablets

Triamterene belongs to the group of medicines known as potassium-sparing diuretics. A diuretic is a medicine which increases the amount of urine that you pass out from your kidneys. They are often referred to as 'water' tablets. Triamterene is called a potassium-sparing diuretic because, unlike some other diuretics, it does not cause your body to lose potassium. It is used to treat water retention (oedema), and it is also given alongside other diuretics to reduce the amount of potassium they cause your body to lose.

Oedema occurs when fluid leaks out of your blood vessels, causing swelling in the tissues of your lungs, feet or ankles. This makes you feel breathless and your legs feel puffy. It is commonly caused by heart failure or liver disease. Triamterene prevents the build-up of this fluid by increasing the amount of urine your kidneys produce.

In the UK, triamterene is only available in combination with another diuretic medicine called clortalidone. This combination can help cut down on the number of tablets you need to take each day.

Before taking triamterene

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking triamterene it is important that your doctor knows:

  • Se sei incinta o stai allattando.

  • If you have problems with the way your kidneys work, or any difficulty passing urine.

  • Se hai problemi con il funzionamento del tuo fegato.

  • Se hai il diabete.

  • If you have attacks of gout.

  • If you have been told by a doctor that you have high levels of potassium in your blood.

  • If you have a problem with your adrenal glands, called Morbo di Addison.

  • Se stai assumendo altri medicinali. Questo include qualsiasi medicinale disponibile per l'acquisto senza prescrizione, così come i medicinali a base di erbe e complementari.

  • Se hai mai avuto una reazione allergica a un medicinale.

How to take triamterene

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about triamterene and will also provide you with a full list of side-effects which you could experience from taking it.

  • Take triamterene exactly as your doctor tells you to. It is usual, to begin with, to take 3-5 capsules a day divided into two doses, one dose with your breakfast and the other at lunchtime. After the first week or so, your doctor is likely to ask you to take the capsules on alternate days only. The directions for taking your doses will be printed on the label of the pack to remind you about what the doctor said to you.

  • Diuretics are best taken no later than mid-afternoon. This is because you will find you may need to go to the toilet a couple of times after taking it and this will disturb your sleep if you take it too late in the day.

  • Swallow the capsules with a drink of water. You can take triamterene either with or without food.

  • If you forget to take a dose of triamterene, take it when you remember if it is only a few hours late. If it is after mid-afternoon, leave out the forgotten dose completely and take your next dose when it is due. Do not take two doses at the same time to make up for a missed dose.

Ottenere il massimo dal tuo trattamento

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. The balance of salts in your blood may be upset by triamterene so your doctor may want you to have a blood test from time to time to check for this.

  • Diuretics help you to lose water, so you can breathe and move more easily. If, however, you lose too much fluid, you may become lacking in fluid in the body (dehydrated). This will make you feel thirsty and make your skin look and feel dry. Let your doctor know if this happens, as your dose may need to be adjusted.

  • Because triamterene is a potassium-sparing diuretic, you should try to avoid things with a high potassium content, such as 'salt substitutes'. This is so the level of potassium in your body does not become too high.

  • Treatment with diuretics is usually long-term, so continue to take triamterene unless your doctor advises you otherwise.

  • If you buy any medicines 'over the counter', please check with a pharmacist that they are suitable for you to take alongside your prescribed medicines.

  • Triamterene can cause your urine to look slightly blue in some lights - this is harmless and nothing to be concerned about.

Se stai assumendo anche idroclorotiazide in combinazione con questo medicinale

  • Studi hanno suggerito che assumere dosi più elevate di idroclorotiazide per lunghi periodi di tempo potrebbe aumentare il rischio di alcuni tipi di cancro della pelle.

  • Informa il tuo medico se sei mai stato trattato per il cancro della pelle in passato.

  • Informa il tuo medico di eventuali nei nuovi o modificati o segni preoccupanti sulla tua pelle.

  • Usa una crema solare sotto il sole forte. Non usare lettini abbronzanti.

Can triamterene cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the common ones associated with triamterene. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common triamterene side-effects (these affect fewer than 1 in 10 people)

Cosa posso fare se sperimento questo?

Sensazione di malessere (nausea) o vomito

Stick to simple foods - avoid fatty or spicy meals. Try taking the capsules after a meal or a snack

Diarrea

Bevi molta acqua per reintegrare i liquidi persi

Modifiche ai risultati di alcuni esami del sangue

Your doctor will check for this from time to time

If you experience any other symptoms which you think may be due to the capsules, please speak with your doctor or pharmacist for further advice.

How to store triamterene

  • Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.

  • Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.

Informazioni importanti su tutti i medicinali

Informazioni importanti su tutti i medicinali

Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.

Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.

Se devi sottoporti a un'operazione o a un trattamento dentale, informa la persona che esegue il trattamento quali medicinali stai assumendo.

Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.

Se hai domande su questo medicinale, chiedi al tuo farmacista.

Segnala effetti collaterali di un medicinale o vaccino

Se si verificano effetti collaterali, è possibile segnalarli online tramite il Sito web Yellow Card.

verificatore di sintomi

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Controlla le possibili interazioni tra farmaci, integratori e alimenti prima di assumerli insieme.

Domande frequenti

What is the typical starting dosage for triamterene and how often is it taken?

Initially, it is usual to take 3-5 capsules a day, divided into two doses, one with breakfast and the other at lunchtime. After the first week or so, your doctor may suggest taking the capsules on alternate days only.

Why is it recommended to take diuretics no later than mid-afternoon?

Diuretics are best taken no later than mid-afternoon because they increase the amount of urine you pass. Taking them later in the day could lead to needing to go to the toilet a couple of times, which might disturb your sleep.

Is it important to take triamterene with food or can it be taken on an empty stomach?

Triamterene can be taken either with or without food. You should swallow the capsules with a drink of water.

What should I do if I experience nausea or vomiting while taking triamterene?

If you experience nausea or vomiting, try to stick to simple foods and avoid fatty or spicy meals. Taking the capsules after a meal or a snack may also help.

Can triamterene affect the appearance of my urine?

Yes, triamterene can cause your urine to look slightly blue in some lights. This is a harmless side effect and not a cause for concern.

What should I do if I need to have surgery or dental treatment while taking triamterene?

It's important to inform the person carrying out any surgery or dental treatment about all the medicines you are currently taking, including triamterene.

Is triamterene a diuretic?

Yes, triamterene is a type of medicine known as a potassium-sparing diuretic. It increases the amount of urine you pass from your kidneys.

Ulteriori letture e riferimenti

Informazioni sull'autoreVisualizza il profilo completo

Immagine dell'autore

Michael Stewart, MRPharmS

Responsabile Revisione Foglietti Illustrativi – Contrattista, Farmacista

BPharm (Hons), MRPharmS

Michael è un farmacista comunitario che esercita nelle Midlands e nel South Yorkshire con oltre 20 anni di esperienza nel consigliare su farmaci e condizioni mediche. Ha una solida esperienza nella formazione sanitaria, avendo prodotto e tenuto corsi di formazione per team di farmacia e personale di strutture di assistenza residenziale, inclusi infermieri. Ha anche contribuito a consigli consultivi farmaceutici per la gestione di condizioni a bassa gravità nella comunità.

Informazioni sul recensore

Immagine dell'autore

Sid Dajani

Sultan Dajani si è laureato alla London School of Pharmacy nel 1994 ed è diventato il più giovane membro eletto del consiglio della Royal Pharmaceutical Society dalla sua fondazione nel 1842.

Storia dell'articolo

Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.

  • Next review due: 5 May 2028
  • 5 May 2025 | Ultima versione

    Ultimo aggiornamento di

    Michael Stewart, MRPharmS

    Revisione paritaria di

    Sid Dajani
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