Compresse di Quinapril
Revisione paritaria di Sid DajaniUltimo aggiornamento di Michael Stewart, MRPharmSUltimo aggiornamento 15 Feb 2025
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Quinapril is generally well tolerated but if you develop a troublesome cough, you must let your doctor know.
The first dose in particular can make you feel dizzy. It is best taken just before you go to sleep.
Some painkillers and indigestion remedies could interfere with quinapril. Ask your pharmacist for advice before you buy any medicines 'over the counter'.
Nota dell'autore clinico: Michael Stewart 15/11/2018: Following an MHRA update, new advice has been added to this leaflet for people also taking the blood pressure medicine hydrochlorothiazide. Hydrochlorothiazide is only available in the UK in combination with other medicines used to treat high blood pressure. It may be available on its own in other countries. For more information see the warning below in 'can this medicine cause problems?' or view the Avviso MHRA.
A colpo d'occhio
Quinapril is a medicine used to treat high blood pressure and heart failure.
It works by widening blood vessels and helping to reduce excess fluid in the blood.
Take quinapril exactly as your doctor tells you, usually once daily.
Your first dose may make you feel dizzy, so consider taking it at bedtime.
Common side-effects include dizziness and a dry cough.
Stop taking quinapril and seek immediate medical help if you have swelling of your face, mouth, tongue, or throat.
About quinapril
Tipo di medicinale | An angiotensin-converting enzyme (ACE) inhibitor |
Utilizzato per | High blood pressure (hypertension); heart failure |
Chiamato anche | Accupro® (discontinued); Accupril® (USA) |
Disponibile come | Compresse |
Quinapril belongs to a class of medicines called angiotensin-converting enzyme inhibitors, or ACE inhibitors. You may have been prescribed it to reduce pressione alta (ipertensione), or to treat insufficienza cardiaca. Your doctor will tell you why it has been prescribed for you.
ACE inhibitors like quinapril prevent your body from creating a hormone known as angiotensin II. They do this by blocking (inhibiting) a chemical called angiotensin-converting enzyme. They widen your blood vessels and help to reduce the amount of water put back into your blood by your kidneys.
These actions help to decrease blood pressure. Although people with high blood pressure often do not feel unwell, if left untreated, high blood pressure can harm the heart and damage blood vessels, leading to a heart attack or stroke.
Heart failure is a condition in which your heart does not work as well as it should. Because of this, there may be too much circulating fluid in your blood vessels. Quinapril helps to reduce this. It also appears to have a protective effect on the heart.
You may be prescribed quinapril on its own, or alongside other medicines to help your condition. The brand of quinapril called Accuretic® also contains a medicine called hydrochlorothiazide. This brand can be prescribed for people with high blood pressure. Combination brands like this help to reduce the total number of tablets you need to take each day.
Before taking quinapril
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking quinapril it is important that your doctor knows:
Se sei incinta o stai allattando.
If you have problems with the way your kidneys work, or any problems with the way your liver works.
If you are lacking in fluid in the body (dehydrated) - for example, if you have had diarrhoea or sickness very recently.
If you have been told you have a build-up of fatty deposits on the walls of your arteries, a condition called atherosclerosis.
If you have a particular type of poor circulation called peripheral arterial disease.
If you have collagen vascular disease. This includes conditions such as systemic lupus erythematosus (SLE) and scleroderma.
If you have been told you have a problem with the way your heart pumps blood
If you have been told you have heart muscle disease (cardiomyopathy), problems with the way your heart pumps blood, or narrowing of the main blood vessel from your heart (aortic stenosis).
If you have been told you have a low level of sodium in your blood.
If you have ever had a reaction where your face, tongue or throat swells (angio-oedema).
If you are having desensitisation treatment to protect against bee and wasp stings.
If you are having dialysis treatment, or treatment to remove cholesterol from your blood by a machine (LDL apheresis).
Se stai assumendo altri medicinali. Questo include qualsiasi medicinale che stai assumendo e che è disponibile per l'acquisto senza prescrizione medica, così come i medicinali a base di erbe e complementari.
If you have ever had an allergic or unusual reaction to any other ACE inhibitor (such as lisinopril, ramipril or enalapril), or to any other medicine.
How to take quinapril
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about quinapril and will provide you with a full list of side-effects which you may experience from taking it.
Take the tablets exactly as your doctor tells you to. Quinapril is usually taken once daily, but it can also be prescribed as a twice-daily dose. Your dose will be printed on the label of the pack of tablets to remind you about what the doctor said to you.
Your doctor is likely to advise you to take your very first dose at bedtime. This is because the first dose can make you feel dizzy.
After the first dose, you can take quinapril at a time of day you find easy to remember, but try to take it at the same times of day each day. This will help you to remember to take your doses regularly. You can take quinapril tablets either with or without food. Swallow the tablet with a drink of water.
Se dimentichi di prendere una dose, prendila appena te ne ricordi (a meno che non sia quasi ora della dose successiva, in tal caso salta la dose dimenticata e prendi la dose successiva come di consueto). Non prendere due dosi insieme per compensare una dose dimenticata.
Ottenere il massimo dal tuo trattamento
Try to keep your regular appointments with your doctor. This is so your progress can be monitored. Your doctor may want you to have some blood tests from time to time to check that your kidneys are working well.
Each time you collect a prescription, check to make sure the tablets look the same as you have had before. This is because there are several strengths of tablet. If you have any questions about your tablets, please ask your pharmacist for advice.
It is very important that you follow any dietary and lifestyle advice that you are given by your doctor. This may include advice about eating a healthy diet, not smoking, and taking regular exercise.
If you buy any medicines, check with a pharmacist that they are suitable to take with quinapril. This is because some medicines (such as anti-inflammatory painkillers and indigestion remedies) could interfere with your treatment.
It is likely that your doctor will advise that you do not use salt substitutes while you are taking quinapril. These products have a high content of potassium which could be harmful for you.
If you drink alcohol, ask your doctor for advice about drinking alcohol while you are on quinapril. Alcoholic drinks can make you feel light-headed or dizzy, and they may not be advisable for you.
If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking quinapril tablets. This is because some anaesthetics could cause your blood pressure to drop too low.
Treatment with quinapril is usually long-term unless you experience an adverse effect. Continue to take the tablets unless you are advised otherwise.
Can quinapril cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with quinapril. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common quinapril side-effects (these affect fewer than 1 in 10 people) | Cosa posso fare se sperimento questo? |
Feeling light-headed or dizzy, especially when standing up | Getting up more slowly should help. If you begin to feel dizzy, lie down so that you do not faint, then sit for a few moments before standing. If this continues beyond the first few days, speak with your doctor. Do not drive and do not use tools or machines while you feel dizzy |
Dry irritating cough | If this continues, speak with your doctor, as an alternative medicine may be better for you |
Mal di testa, altri dolori e fastidi | Chiedi al tuo farmacista di consigliare un antidolorifico adatto |
Feeling sick (nausea) or being sick (vomiting), indigestion, tummy (abdominal) pain, diarrhoea | Stick to simple foods - avoid rich and spicy meals |
Throat infections, runny nose, tingling feelings in your hands or toes, problems sleeping or feeling tired | Parla con il tuo medico se uno di questi diventa problematico |
Importante: if you experience any of the following rare but serious symptoms, stop taking quinapril and contact your doctor for advice straightaway:
Any difficulty breathing, or swelling of your face, mouth, tongue or throat. These are signs of an allergic reaction.
Any yellowing of your skin or whites of your eyes. These may be signs of jaundice which is a rare side-effect.
A severe skin rash.
Se stai assumendo anche idroclorotiazide in combinazione con questo medicinale:
Studi hanno suggerito che assumere dosi più elevate di idroclorotiazide per lunghi periodi di tempo potrebbe aumentare il rischio di alcuni tipi di cancro della pelle.
Informa il tuo medico se sei mai stato trattato per il cancro della pelle in passato.
Informa il tuo medico di eventuali nei nuovi o modificati o segni preoccupanti sulla tua pelle.
Usa una crema solare sotto il sole forte. Non usare lettini abbronzanti.
Se si verificano altri sintomi che ritieni possano essere dovuti alle compresse, parla con il tuo medico o farmacista per ulteriori consigli.
How to store quinapril
Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.
Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.
Informazioni importanti su tutti i medicinali
Informazioni importanti su tutti i medicinali
Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.
Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.
Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.
Se hai domande su questo medicinale, chiedi al tuo farmacista.
Segnala effetti collaterali di un medicinale o vaccino
Se si verificano effetti collaterali, è possibile segnalarli online tramite il Sito web Yellow Card.

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Controlla le possibili interazioni tra farmaci, integratori e alimenti prima di assumerli insieme.
Domande frequenti
What is the significance of the brand name Accupro being discontinued, and does this affect current quinapril users?
The article notes that Accupro is a discontinued brand name for quinapril. This information primarily serves to clarify that while the brand may no longer be available, the active medication, quinapril, is still in use and prescribed under different names or as a generic. It doesn't affect the availability or efficacy of quinapril for current users, who would receive it under its current brand (Accupril in the USA) or as a generic.
How does quinapril specifically protect the heart in individuals with heart failure?
In cases of heart failure, where the heart isn't working as efficiently as it should, quinapril helps by reducing the amount of circulating fluid in the blood vessels. Beyond this, the article states that quinapril also 'appears to have a protective effect on the heart,' contributing to better heart function in this condition.
What are collagen vascular diseases, and why is it important for my doctor to know if I have one before prescribing quinapril?
Collagen vascular diseases are a group of conditions that affect the body's connective tissues and can include diseases like systemic lupus erythematosus (SLE) and scleroderma. It's crucial for your doctor to be aware if you have such a condition because these illnesses can affect various organs, and quinapril's actions or potential side effects might interact in specific ways that require extra medical care or an alternative treatment.
What should I do if I am prescribed quinapril and also have a low level of sodium in my blood?
If you have a low level of sodium in your blood, it is important to inform your doctor before starting quinapril. The article highlights this as a condition requiring your doctor's awareness, suggesting that it might influence the suitability of quinapril for you or necessitate extra monitoring and care during your treatment.
If I am undergoing desensitisation treatment for bee and wasp stings, why do I need to inform my doctor before taking quinapril?
It is important to tell your doctor if you are having desensitisation treatment to protect against bee and wasp stings. The article indicates that this is a specific circumstance where your doctor needs to be aware of your medical history before prescribing quinapril, suggesting potential interactions or considerations during your treatment with both quinapril and the desensitisation therapy.
Can taking quinapril affect cholesterol-lowering treatments like LDL apheresis?
Yes, if you are undergoing treatment to remove cholesterol from your blood by a machine, known as LDL apheresis, it is important to inform your doctor. The article states this as a condition your doctor needs to know about before you start quinapril, suggesting potential interactions or requiring extra care during combined treatments.
How can I tell if a cough I'm experiencing is a common side effect of quinapril or something more serious?
A dry, irritating cough is listed as a common side effect of quinapril, affecting fewer than 1 in 10 people. If you develop a cough that continues or becomes troublesome, the article advises speaking with your doctor, as an alternative medicine might be more suitable for you. This distinguishes it from more serious reactions and offers a clear course of action.
Why is it important to check the appearance of my quinapril tablets each time I get a new prescription?
You should check the appearance of your quinapril tablets with each new prescription because there are several strengths of the tablet available. The article advises doing this to ensure you have received the correct dosage. If you notice any differences or have questions, you should ask your pharmacist for advice.
Ulteriori letture e riferimenti
- Medicinali Completi BNF 89ª Edizione; Associazione Medica Britannica e Società Farmaceutica Reale di Gran Bretagna, Londra.
Informazioni sull'autoreVisualizza il profilo completo

Michael Stewart, MRPharmS
Responsabile Revisione Foglietti Illustrativi – Contrattista, Farmacista
BPharm (Hons), MRPharmS
Michael è un farmacista comunitario che esercita nelle Midlands e nel South Yorkshire con oltre 20 anni di esperienza nel consigliare su farmaci e condizioni mediche. Ha una solida esperienza nella formazione sanitaria, avendo prodotto e tenuto corsi di formazione per team di farmacia e personale di strutture di assistenza residenziale, inclusi infermieri. Ha anche contribuito a consigli consultivi farmaceutici per la gestione di condizioni a bassa gravità nella comunità.
Informazioni sul recensore

Sid Dajani
Sultan Dajani si è laureato alla London School of Pharmacy nel 1994 ed è diventato il più giovane membro eletto del consiglio della Royal Pharmaceutical Society dalla sua fondazione nel 1842.
Storia dell'articolo
Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.
Articolo disponibile anche in Inglese, Tedesco, Spagnolo, Francese, Italiano, Portoghese, Hindi, Ebraico, Arabo, and Svedese.
Prossima revisione prevista: 15 Feb 2028
15 Feb 2025 | Ultima versione

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