Glyburide per il diabete

About glyburide

Insulin is a hormone which is made naturally in your body, in the pancreas. It helps to control the levels of sugar (glucose) in your blood. If your body does not make enough insulin, or if it does not use the insulin it makes effectively, this results in the condition called diabete (diabete mellito).

Persone con diabete need treatment to control the amount of sugar in their blood. This is because good control of blood sugar levels reduces the risk of complications later on. Some people can control the sugar in their blood by making changes to the food they eat but, for other people, medicines like glyburide are given alongside the changes in diet.

Glyburide (also know as glibenclamide) works by increasing the amount of insulin that your pancreas produces. This helps to reduce the amount of sugar in your blood.

Glyburide is also available in combination with another antidiabetic medicine called metformina. This combination reduces the number of tablets you need to take each day.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking glyburide it is important that your physician knows:

• Se sei incinta, stai cercando di avere un bambino o stai allattando.

• Se hai problemi con il funzionamento del tuo fegato o con il funzionamento dei tuoi reni.

• If you have been told you have porphyria or glucose 6-phosphate dehydrogenase (G6PD) deficiency. These are rare inherited disorders.

• Se stai assumendo altri medicinali. Questo include qualsiasi medicinale che stai assumendo e che è disponibile per l'acquisto senza prescrizione medica, così come i medicinali a base di erbe e complementari.

• Se hai mai avuto una reazione allergica a un medicinale.

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about glyburide tablets and will provide you with a full list of the side-effects which you may experience from taking them.

• Take glyburide exactly as your physician tells you to. The usual starting dose is 5 mg daily. It is prescribed as a single dose to be taken with, or immediately after, breakfast.

• Depending on your blood sugar (glucose) levels, your daily dose may need to be increased. Your physician will do this slowly, usually increasing by one 2.5 mg tablet each week. Your blood sugar levels will need to be tested regularly.

• If you need higher doses your physician may ask you to take glyburide twice each day. If this happens take each dose with a meal or snack and try to space your doses evenly.

• Different manufacturers' products may contain different amounts of glyburide and have different recommended doses. Each time you get a prescription make sure you receive the same strength of tablet as before. Ask the pharmacist for advice if you are unsure.

• If you forget to take a dose at the usual time, take it with your next meal. If you do not remember until the following day, skip the missed dose. Do not take two doses on the same day to make up for a forgotten dose.

• It is important that you keep your regular physician's and laboratory appointments. This is so that your progress can be monitored. You will need regular check-ups with an eye clinic and a foot clinic as well as with your physician and diabetes clinic.

• Your physician may recommend that you test for sugar (glucose) in your blood regularly to check that your diabetes is being controlled. Your physician will show you how to do this.

• If you have been given advice by your physician about changes to your diet, stopping smoking or taking regular exercise, it is important for you to follow the advice you have been given.

• Make sure you know what it feels like if your blood sugar drops too low. This is known as hypoglycemia, or a 'hypo'. The first signs of hypoglycemia are feeling shaky or anxious, sweating, looking pale, feeling hungry, having a feeling that your heart is pounding (palpitations), and feeling dizzy. If this happens, eat something containing sugar, such as dextrose tablets, sugary candy or a sugary soda (non-diet). Then follow this up with a snack such as a sandwich or a banana.

• Low blood sugar can occur if you miss a meal, if you exercise more than usual, if you are ill, or if you drink alcohol.

• Do not drink alcohol, as it can affect the control of your blood sugar. Ask your physician if you need further advice about this.

• Se sei un conducente, dovresti prestare particolare attenzione, poiché la tua capacità di concentrazione potrebbe essere compromessa se il tuo diabete non è ben controllato. Potresti essere consigliato di controllare i livelli di zucchero nel sangue prima di viaggiare e di avere uno spuntino con te durante i lunghi viaggi.

• All US states have special licensing laws for drivers with medical conditions. You may be required to report your diabetes to local agencies. Ask your physician for advice about the laws in your state.

• If you get unusually thirsty, pass urine more frequently than normal, or feel very tired, you should let your physician know. These are signs that there is too much sugar in your blood and your treatment may need adjusting.

• Check with your physician before taking up any new physical exercise, as this will have an effect on your blood sugar levels and you may need to check your blood levels more regularly.

• If you are due to have an operation or dental treatment, you should tell the person carrying out the treatment that you have diabetes and give them a list of the medicines you are taking.

• Se acquisti dei medicinali, verifica sempre con un farmacista che siano adatti a te.

• Treatment for diabetes is usually lifelong. Continue to take the tablets unless you are advised otherwise by your physician.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with glyburide. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your physician or pharmacist if any of the following continue or become troublesome.

Se si verificano altri sintomi che ritieni possano essere dovuti a questo medicinale, parla con il tuo medico o farmacista.

• Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.

• Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.