Cicloserina per la tubercolosi
Revisione paritaria di Sid DajaniUltimo aggiornamento di Michael Stewart, MRPharmSUltimo aggiornamento 1 giu 2025
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Cycloserine is one of several medicines you will need to take to treat tuberculosis (TB).
You will need to have regular blood tests while you are taking the medicine.
It is important that you take your doses regularly, every 12 hours.
A colpo d'occhio
Cycloserine is a medicine used to treat tuberculosis (TB).
It is prescribed when other common TB medicines are unsuitable or ineffective.
Take capsules regularly, usually twice a day, with or without food.
Do not drink alcohol or stop taking cycloserine without your doctor's advice.
Tell your doctor if you experience severe headaches, dizziness, confusion, or fits.
About cycloserine
Tipo di medicinale | An antituberculosis medicine |
Utilizzato per | Tubercolosi (TB) |
Disponibile come | Capsule |
Cycloserine is used to treat tubercolosi (TB). TB is a bacterial infection which mostly affects the lungs, but which can affect any part of your body. TB is treatable with a course of medicines which usually lasts for six months. You will need to take several medicines to treat TB - cycloserine is one of the medicines used. Cycloserine will be prescribed for you if other more frequently prescribed antituberculosis medicines are either not suitable for you, or have not been effective for you.
Cycloserine works by acting on the cell walls of the germs (bacteria) responsible for the TB. The cell walls do not form correctly which causes them to break, killing the bacteria.
Cycloserine will be prescribed for you by a doctor who specialises in the treatment of TB. It is important that you take it regularly.
Before taking cycloserine
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking cycloserine it is important that your doctor knows:
Se sei incinta o stai allattando.
Se bevi molto alcol.
If you have any mental health problems, such as anxiety, depression or psychosis.
Se hai problemi con il funzionamento del fegato o con quello dei reni.
If you have a condition that causes fits, such as epilepsy.
Se hai un raro disturbo ereditario del sangue chiamato porfiria.
Se stai assumendo altri medicinali. Questo include qualsiasi medicinale disponibile per l'acquisto senza prescrizione, così come i medicinali a base di erbe e complementari.
Se hai mai avuto una reazione allergica a un medicinale.
How to take cycloserine
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about cycloserine and will provide you with a full list of the side-effects which you could experience from taking it.
Take the capsules exactly as your doctor tells you to. As a guide, the usual dose to begin with in adults is one capsule twice a day, taken 12 hours apart (morning and evening). After two weeks, your dose may be increased to two capsules twice a day, depending on the result of a blood test.
Try to take your doses of cycloserine at the same times of day each day, as this will help you to remember to take your doses regularly. You can take the capsules either with or without food.
If you forget to take a dose, take it as soon as you remember. Try to take the correct number of doses each day, but do not take two doses at the same time to make up for a missed dose.
Ottenere il massimo dal tuo trattamento
It is important that you keep your regular appointments with your doctor, or clinic. This is so your doctor can check on your progress. Your doctor will want you to have blood tests during the treatment, to make sure you have just the right amount of the medicine in your bloodstream. For some people, these tests can be as regular as once a week.
Continue to take the capsules regularly - do not stop taking cycloserine unless your doctor tells you to stop. This is because it is important for you to complete the course of medicine so that the infection does not come back. Your treatment will last for several months.
Do not to drink alcohol while you are on cycloserine. Cycloserine causes drowsiness, and drinking alcohol will increase the chance that you experience this side-effect. It also increases the risk of more serious side-effects, such as fits (convulsions).
Cycloserine can stop the oral typhoid vaccine from working properly. If you are due to have any vaccinations, make sure that the person treating you knows you are taking this medicine. Also, if you are due to have an operation or any dental treatment, you should tell the person carrying out the treatment that you are taking cycloserine for TB.
If you buy any medicines 'over the counter', check with a pharmacist that they are suitable for you to take alongside your prescribed medicines.
Can cycloserine cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with cycloserine. You will find a full list in the manufacturer's information leaflet supplied with the medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Cycloserine side-effects | Cosa posso fare se sperimento questo? |
Mal di testa | Drink plenty of water and ask your pharmacist to recommend a suitable painkiller. Let your doctor know if the headache continues |
Feeling dizzy or sleepy, a spinning sensation (called vertigo) | Non guidare e non utilizzare strumenti o macchinari. Non bere alcolici |
Feeling shaky, fits, feeling confused, mood or character changes, allergic skin rashes | Let your doctor know as soon as possible if you experience any of these |
Changes to the results of some blood tests (such as those checking your liver and blood) | Il tuo medico monitorerà questi aspetti |
If you experience any other symptoms which you think may be due to the capsules, please speak with your doctor or pharmacist for further advice.
How to store cycloserine
Tenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.
Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.
Informazioni importanti su tutti i medicinali
Informazioni importanti su tutti i medicinali
Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati immediatamente al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.
Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.
Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.
Se hai domande su questo medicinale, chiedi al tuo farmacista.
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Domande frequenti
What happens if I accidentally take two doses at once?
If you forget to take a dose, you should take it as soon as you remember. However, it's important not to take two doses at the same time to make up for a missed dose. If you accidentally take too much, or suspect an overdose, you should go to the accident and emergency department of your local hospital immediately and take the medicine container with you.
What should I do if I notice changes in my mood or behaviour while taking cycloserine?
If you experience serious side-effects like feeling shaky, having fits, feeling confused, or noticing changes in your mood or character, you should let your doctor know as soon as possible. Your doctor will monitor your progress and blood tests throughout your treatment.
Will I have to take cycloserine for the entire six-month TB treatment?
Cycloserine is one of the medicines used to treat TB, and your treatment course for TB will last for several months. It is important to continue taking cycloserine regularly and not to stop unless your doctor tells you to. This ensures the infection does not return.
Can I drive or operate machinery while taking cycloserine?
Cycloserine can cause side-effects such as feeling dizzy, sleepy, or experiencing a spinning sensation (vertigo). If you experience these, you should not drive or use tools or machines.
What should I do with any leftover cycloserine capsules once my treatment is finished?
You should not keep out-of-date or unwanted medicines. Take any unused cycloserine to your local pharmacy, and they will dispose of them for you.
Ulteriori letture e riferimenti
- Manufacturer's PIL, Cycloserine 250 mg capsules; Neon Healthcare Ltd, The electronic Medicines Compendium. Dated May 2023.
- Medicinali Completi BNF 89ª Edizione; Associazione Medica Britannica e Società Farmaceutica Reale di Gran Bretagna, Londra.
Informazioni sull'autoreVisualizza il profilo completo

Michael Stewart, MRPharmS
Responsabile Revisione Foglietti Illustrativi – Contrattista, Farmacista
BPharm (Hons), MRPharmS
Michael è un farmacista comunitario che esercita nelle Midlands e nel South Yorkshire con oltre 20 anni di esperienza nel consigliare su farmaci e condizioni mediche. Ha una solida esperienza nella formazione sanitaria, avendo prodotto e tenuto corsi di formazione per team di farmacia e personale di strutture di assistenza residenziale, inclusi infermieri. Ha anche contribuito a consigli consultivi farmaceutici per la gestione di condizioni a bassa gravità nella comunità.
Informazioni sul recensore

Sid Dajani
Sultan Dajani si è laureato alla London School of Pharmacy nel 1994 ed è diventato il più giovane membro eletto del consiglio della Royal Pharmaceutical Society dalla sua fondazione nel 1842.
Storia dell'articolo
Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.
Articolo disponibile anche in Inglese, Tedesco, Spagnolo, Francese, Italiano, Portoghese, Hindi, Ebraico, Arabo, and Svedese.
Prossima revisione prevista: 1 giu 2028
1 giu 2025 | Ultima versione

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