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Clobetasol propionate for severe inflammatory skin conditions

Clarelux, ClobaDerm, Dermovate, Etrivex

You only need to use a small amount of this preparation. Apply a small amount just to the areas affected, and then massage it gently into the skin.

Topical corticosteroids should not be used for long periods of time or on large areas of the body, especially in children. This is due to the risk of serious side-effects with long-term use.

As a guide, clobetasol should not be used continuously for more than 5 days in children and 7 days in adults, unless your doctor gives specific instructions to do so.

Clobetasol propionate (unless combined with an antibacterial agent) should not be used on any infected areas of skin.

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About clobetasol propionate

Tipo di medicinale

A very potent topical corticosteroid

Utilizzato per

Inflammatory skin conditions such as severe eczema and dermatitis

Chiamato anche

Clarelux®; ClobaDerm®; Dermovate®; Etrivex®

Disponibile come

Cream, ointment, foam, scalp application and shampoo

Clobetasol propionate is classed as a very potent topical corticosteroid. Topical corticosteroids are also referred to as steroidi topici. Topical steroids are used in addition to moisturisers (emollients) for treating inflammatory skin conditions such as eczema e dermatite. A topical steroid is used when patches of eczema or dermatitis flare up. Clobetasol propionate relieves the symptoms of a flare-up by reducing inflammation, itching and redness. It is not a cure for the condition, but it will help to relieve the symptoms.

Specialist skin doctors may on occasion prescribe a short course of clobetasol propionate for the treatment of psoriasis, although it is not generally recommended for this skin condition. Clobetasol propionate is not recommended for use in children, although again, it may be prescribed for a child by a specialist doctor under certain circumstances.

Clobetasol propionate is available as a number of different preparations. It is likely you will be prescribed a cream if the affected areas of your skin are moist or weeping, or an ointment if your skin is dry. It is also available as a shampoo and as an application for the scalp.

There is also a preparation available which contains two antibacterial agents called neomycin and nystatin. You may be prescribed this preparation for short-term use if your skin has become infected. It is typically used twice a day for one week only.

To make sure this is the right treatment for you, before you start using clobetasol propionate it is important that your doctor knows:

  • Se hai delle aree di pelle infetta.

  • Se hai la rosacea o l'acne.

  • Se sei incinta o stai allattando.

  • Se hai mai avuto una reazione allergica a una preparazione per la pelle.

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  • Before you start using the preparation, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about topical steroids and will give you full instructions for using the preparation you have been given. It will also provide you with a list of the side-effects that you may experience.

  • Apply a small amount of cream/ointment to the areas of skin which are inflamed. Then gently rub it into the skin until it has disappeared. Do not use clobetasol propionate on any open sores or areas of infected skin unless you have a preparation which contains antibacterial agents (clobetasone with neomycin and nystatin). If you are using this preparation, use it regularly twice daily for one week only, unless you have been directed otherwise by your doctor.

  • The amount of topical steroid cream/ointment that you should apply is commonly measured by fingertip units (FTUs). One FTU is the amount of cream or ointment that is squeezed out along an adult's fingertip (that is, from the very end of the finger to the first crease in the finger). As a guide, one FTU is enough to cover an area twice the size of an adult hand. Your doctor will give you an idea of how many FTUs you will need to cover the area of your skin which is affected.

  • If you are using a scalp application, apply a few drops of liquid or a small amount of foam to the affected areas of your scalp, rub it in gently, and then allow the areas to dry again naturally. If you are using Etrivex® shampoo, apply a small amount to the affected areas of your hair when it is dry, massage it in gently, and then rinse it off after 15 minutes. As a guide to how much to use, half a tablespoon of shampoo (7.5 ml) is sufficient to cover the whole of your scalp.

  • If you are using Clarelux® cutaneous foam, hold the container upside-down so the nozzle is pointing downwards. Press the button to deliver a teaspoon-sized amount of foam directly onto the affected skin and gently massage the area until the foam disappears. Try not to spray the foam into your hands first as it will quickly start to melt. Avoid contact with the eyes, nose and mouth.

  • Your doctor will tell you how often to apply clobetasol propionate. It must not be applied more than twice a day, and once a day is often sufficient.

  • Se stai usando più di un corticosteroide topico, assicurati di sapere quando e dove usare ciascuno. Se hai dubbi, consulta il tuo medico o chiedi ulteriori consigli al tuo farmacista.

  • After you have applied clobetasol propionate, remember to wash your hands (unless your hands are the treated area).

  • If you are using clobetasol propionate for psoriasis, make sure you follow your doctor's instructions carefully. It should not be used for large areas of psoriasis or for long periods of time, as these can cause your symptoms to flare up again afterwards.

  • Clobetasol propionate is not suitable for use in children unless it is has been advised by a skin specialist. This is because children are particularly susceptible to side-effects from strong topical steroids. The main concern is for children who need frequent courses, as it can have an effect on their growth and this will need to be monitored. If your child has been prescribed clobetasol propionate, follow the directions you have been given very carefully, and do not use it for longer than you have been told to. As a general rule, it should not be used for more than five days in children.

  • If you are using a moisturiser along with this preparation, apply the moisturiser first. Then wait 10-15 minutes before applying clobetasol propionate. This allows time for the moisturiser to be absorbed before the topical corticosteroid is applied. Your skin should be moist but not slippery when you apply clobetasol propionate.

  • Do not use clobetasol propionate on your face.

  • Se non diversamente consigliato dal medico, non applicare bendaggi o medicazioni sull'area trattata, poiché ciò aumenterà l'assorbimento del preparato e il rischio di effetti indesiderati.

  • Continue to use clobetasol propionate until the flare-up is controlled, and then stop it. A course of treatment for 7-14 days is usually sufficient. If your symptoms have not improved after this time (or if they get worse), speak again with your doctor for further advice.

  • After you finish using clobetasol propionate, continue to use your moisturiser every day. This will help to prevent a further flare-up. Your doctor may also prescribe a less potent steroid cream for you to use when needed.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. You can reduce the risk of side-effects from topical corticosteroids like clobetasol propionate, by applying the preparation thinly, no more than twice a day, and to the affected areas only.

Side-effects of clobetasol propionate

Cosa posso fare se sperimento questo?

Una sensazione di bruciore o prurito

Questi possono verificarsi nei primi giorni ma di solito migliorano dopo

Assottigliamento della pelle, smagliature permanenti, dermatite allergica da contatto, acne, rosacea e crescita dei peli nel sito di applicazione

These would normally only affect you if you use clobetasol propionate for long periods of time

Clobetasol propionate may get through your skin and into your bloodstream

This usually causes no problem unless you use clobetasol propionate regularly on large areas of your skin

If you experience any other symptoms which you think may be due to clobetasol propionate, speak with your doctor or pharmacist for further advice.

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  • Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.

Informazioni importanti su tutti i medicinali

Assicurati che la persona che prescrive questa medicina sia a conoscenza di tutte le altre medicine che stai assumendo o usando. Questo include farmaci acquistati, nonché rimedi erboristici e omeopatici.

Prima di usare questo medicinale, informi il suo medico se ha mai avuto una reazione allergica dopo aver assunto o utilizzato qualsiasi medicinale.

Non utilizzare mai più della dose prescritta. Se sospetti che qualcuno abbia ingerito accidentalmente parte del medicinale, contatta il pronto soccorso del tuo ospedale locale per ricevere consigli.

Se devi sottoporti a un'operazione o a un trattamento dentistico, informa la persona che esegue il trattamento su quali medicinali stai assumendo o utilizzando.

Se acquisti dei medicinali, verifica con un farmacista che siano sicuri da assumere insieme agli altri tuoi medicinali.

Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.

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Ulteriori letture e riferimenti

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About the author

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Storia dell'articolo

Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.

  • Prossima revisione prevista: 21 Feb 2027
  • 25 Apr 2024 | Ultima versione

    Ultimo aggiornamento di

    Michael Stewart, MRPharmS

    Revisione paritaria di

    Sid Dajani
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