Chlorphenamine for allergies
Allerief, Hayleve, Piriton
Revisione paritaria di Dr Colin Tidy, MRCGPUltimo aggiornamento di Michael Stewart, MRPharmSUltimo aggiornamento 17 Apr 2023
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Chlorphenamine is an antihistamine. It eases allergic reactions.
The most common side effects are feeling tired or sleepy. If affected, do not drive and do not use tools or machines until you feel better.
Always make sure you follow the dosage directions on the label.
At a glance
Chlorphenamine is an antihistamine used to relieve allergy symptoms like hay fever and skin rashes.
It is available as tablets or oral liquid and can be bought without a prescription.
Common side effects include feeling dizzy or sleepy, blurred vision, and a dry mouth.
It usually starts working within 30 minutes to 1 hour.
Do not drive or use machinery if you feel drowsy after taking it.
Avoid alcohol while taking chlorphenamine as it can worsen drowsiness.
Talk to a doctor or pharmacist if you are pregnant, breastfeeding, or have other health conditions.
In questo articolo:
Video picks for Medicinali per allergie
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Panoramica
Tipo di medicinale | An antihistamine |
Utilizzato per | Allergic conditions |
Chiamato anche | Chlorpheniramine (in US); Allerief®; Hayleve®; Piriton® |
Disponibile come | Compresse, medicina liquida orale e iniezione |
What is chlorphenamine used for?
Torna ai contenutiChlorphenamine is a type of antistaminico used to relieve allergies such as:
Food allergies.
Drug allergies.
Itching caused by infections such as varicella.
It is also given to treat a type of allergic reaction called anafilassi, which is a medical emergency.
Chlorphenamine is available on prescription, or you can buy it without a prescription at pharmacies.
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How does chlorphenamine work?
Torna ai contenutiChlorphenamine works by blocking the effects of histamine - a chemical that is released when the body is exposed to substances such as pollen, pet fur, peanuts, shellfish or insect bites.
Histamine causes allergic symptoms such as swelling, skin rashes, sneezing, watery eyes, and a runny or blocked nose. Chlorphenamine relieves allergic symptoms like these.
Side effects of chlorphenamine
Torna ai contenutiCommon side effects of chlorphenamine include:
Sensazione di vertigini o sonnolenza.
Visione offuscata.
Mal di testa.
Bocca secca.
Lack of concentration.
Mal di stomaco.
Difficulty peeing (urinating).
Children and people over 65 years of age may be more prone to side effects from chlorphenamine.
You will find a full list of side effects in the manufacturer's information leaflet supplied with your medicine.
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How to manage chlorphenamine side effects
Torna ai contenutiThe unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any continue or become troublesome.
Common chlorphenamine side effects | Cosa posso fare se sperimento questo? |
Feeling dizzy or sleepy, and blurred vision | Do not drive and do not use tools or machines until you feel better. Do not drink alcohol |
Mal di testa | Drink plenty of water and ask your pharmacist to recommend a suitable painkiller. If the headaches continue, stop taking chlorphenamine or ask your doctor for advice. |
Bocca secca | Try sucking sugar-free sweets or chewing sugar-free gum |
Lack of concentration, upset stomach, difficulty peeing, feeling unco-ordinated, irritability (in children) | Parla con il tuo medico se uno di questi diventa problematico |
If you experience any other symptoms which you think may be due to this medicine, speak with your doctor, dentist, or pharmacist for further advice.
Who should not take chlorphenamine?
Torna ai contenutiTo make sure that this is the right treatment for you, before you (or your child) start taking chlorphenamine it is important that you discuss the treatment with a doctor or pharmacist if:
You are pregnant or breastfeeding.
You have a problem with the way your liver works.
You have glaucoma, a condition which causes increased pressure in your eyes.
You have prostate problems, or if you have been experiencing any difficulty peeing.
You know you have a blockage in your small intestines.
You have epilepsy.
Stai assumendo altri medicinali. Questo include qualsiasi medicinale che stai assumendo e che è disponibile per l'acquisto senza prescrizione, così come i medicinali a base di erbe e complementari.
Hai mai avuto una reazione allergica a un medicinale.
How to take chlorphenamine
Torna ai contenutiRead the leaflet included with your medicine before taking chlorphenamine.
Take chlorphenamine exactly as advised by your doctor or pharmacist.
The usual recommended doses are:
Adults and children over 12: 4 mg every 4-6 hours. Maximum: 24 mg daily (12 mg daily if over 65).
Children aged 6-11: 2 mg every 4-6 hours. Maximum: 12 mg daily.
Children aged 2-5: 1 mg every 4-6 hours. Maximum: 6 mg daily.
Children aged 1-23 months: 1 mg twice daily, ideally morning and evening.
If using liquid medicine for children, measure doses carefully using the instructions on the bottle.
You can take chlorphenamine before or after food.
Stop taking chlorphenamine once your symptoms have eased.
If you miss a dose, take the next one as normal. Do not take two doses together.
Ottenere il massimo dal tuo trattamento
Torna ai contenutiChlorphenamine can cause drowsiness. If you feel sleepy, do not drive or use machinery.
Avoid alcohol while taking chlorphenamine, as it can make drowsiness worse.
Tell your doctor or healthcare professional you are taking chlorphenamine before any operation, treatment, or allergy test.
Chlorphenamine may make your skin more sensitive to sunlight. Use sunscreen (SPF 15 or higher) and avoid sunbeds.
Check with a pharmacist before taking other medicines alongside chlorphenamine, as some can increase side effects or interact with antihistamines.
How to store chlorphenamine
Torna ai contenutiTenere tutti i medicinali fuori dalla portata e dalla vista dei bambini.
Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.
Domande frequenti
Torna ai contenutiHow long does chlorphenamine take to work?
Chlorphenamine usually starts working within 30 minutes to 1 hour. Because it is a drowsy antihistamine, some people may feel sleepy soon after taking it.
The effects of chlorphenamine can last for several hours, and drowsiness may continue into the next day in some people.
Can you take chlorphenamine every day?
Chlorphenamine can be taken daily for short-term allergy relief if needed. However, long-term use should only be advised by a doctor or pharmacist.
Always follow the recommended dose and stop taking it once symptoms improve.
Can you drink alcohol while taking chlorphenamine?
It is best to avoid alcohol while taking chlorphenamine. Alcohol can increase drowsiness and make side effects worse.
Can chlorphenamine be taken with other antihistamines?
You should not take chlorphenamine with other antihistamines unless advised by a healthcare professional. Combining antihistamines can increase side effects such as drowsiness.
Can you take chlorphenamine during pregnancy?
Chlorphenamine usually can be taken during pregnancy. However, always let your doctor or midwife know that you are pregnant before taking it.
Informazioni importanti su tutti i medicinali
Torna ai contenutiInformazioni importanti su tutti i medicinali
Non assumere mai più della dose prescritta. Se sospetti che tu o qualcun altro possa aver assunto un sovradosaggio di questo medicinale, recati al pronto soccorso del tuo ospedale locale. Porta con te il contenitore, anche se è vuoto.
Questo medicinale è per te. Non darlo mai ad altre persone, anche se la loro condizione sembra essere la stessa della tua.
Non conservare medicinali scaduti o indesiderati. Portali alla tua farmacia locale che li smaltirà per te.
Se hai domande su questo medicinale, chiedi al tuo farmacista.
Segnala effetti collaterali di un medicinale o vaccino
Se si verificano effetti collaterali, è possibile segnalarli online tramite il Yellow Card website.

Non sei sicuro di mescolare i medicinali?
Controlla le possibili interazioni tra farmaci, integratori e alimenti prima di assumerli insieme.
Domande frequenti
Is chlorphenamine available without a prescription?
Chlorphenamine can be purchased without a prescription from pharmacies. It is also available on prescription from a doctor.
What is the difference between chlorphenamine and chlorpheniramine?
Chlorphenamine is the name used in the UK, while chlorpheniramine is the name used in the US for the same medicine. Both refer to this antihistamine.
Can chlorphenamine be given to very young children?
Yes, chlorphenamine can be given to children aged 1-23 months, with a recommended dose of 1 mg twice daily, ideally morning and evening. For children aged 2-5, the dose is 1 mg every 4-6 hours, with a maximum of 6 mg daily. It's important to measure liquid medicine doses carefully according to the instructions.
Are there any specific activities I should avoid while taking chlorphenamine?
You should avoid driving, operating tools, or using machinery if you feel dizzy or sleepy. It is also advised to avoid alcohol, as it can worsen drowsiness. Additionally, chlorphenamine can make your skin more sensitive to sunlight, so using sunscreen (SPF 15 or higher) and avoiding sunbeds is recommended.
Can I take chlorphenamine if I am scheduled for an operation or allergy test?
You should inform your doctor or any healthcare professional that you are taking chlorphenamine before undergoing any operation, treatment, or allergy test.
What should I do if I miss a dose of chlorphenamine?
If you miss a dose, you should take the next one as normal. Do not take two doses together to make up for the missed dose.
Ulteriori letture e riferimenti
- Manufacturer's PIL, Piriton® Tablets; Haleon UK Trading Limited, The electronic Medicines Compendium. Dated February 2023.
- Manufacturer's PIL, Piriton® Syrup; Haleon UK Trading Limited, The electronic Medicines Compendium. Dated February 2023.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewerView full bio

Dr Colin Tidy, MRCGP
Medico di base, Autore medico
MBBS, MRCGP, MRCP (Paediatrics), DCH
Dr Colin Tidy is an NHS Doctor, based in Oxfordshire.
Storia dell'articolo
Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.
Prossima revisione prevista: 15 Ott 2027
17 Apr 2023 | Ultima versione

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