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Anastrozolo per il cancro al seno

Arimidex

Take one 1 mg tablet each day.

Puoi prendere la compressa prima o dopo i pasti.

The most common side-effects are headache, hot flushes, feeling sick (nausea), rash, joint pain, and feeling weak. These can occur in more than 1 in 10 women who take anastrozole.

At a glance

  • Anastrozole is a hormone treatment for breast cancer in women who have been through the menopause.

  • It works by reducing the amount of oestrogen in the body, which slows cancer cell growth.

  • Do not take anastrozole if you are still having menstrual periods.

  • Take one tablet daily, ideally at the same time each day, before or after a meal.

  • Common side-effects include hot flushes, nausea, and joint aches.

  • You will need regular bone density tests during treatment.

  • If you notice signs of depression, speak with your doctor.

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About anastrozole

Tipo di medicinale

An aromatase inhibitor

Utilizzato per

Cancro al seno

Chiamato anche

Arimidex®

Disponibile come

Compresse

Treatment options for women with cancro al seno include surgery, radiotherapy, chemotherapy and hormone treatment. Often a combination of two or more of these treatments is used. Anastrozole is a hormone treatment.

Some breast cancers need the hormone oestrogen to grow. In women who have been through the menopause, the main source of oestrogen is through the change of sex hormones called androgens into oestrogen. An enzyme called 'aromatase' is needed for this change to occur. Anastrozole works by blocking (inhibiting) this enzyme. This reduces the amount of oestrogen in your body, which slows the growth of the cancer cells.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking anastrozole it is important that your doctor knows:

  • If you are still having menstrual periods - if you have not gone through the menopause you should not take anastrozole.

  • If you have been told you have a loss of bone density (osteoporosis).

  • If you have problems with the way your liver works, or problems with the way your kidneys work.

  • Se hai mai avuto una reazione allergica a un medicinale.

  • If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines. It is particularly important that your doctor knows if you are taking a medicine called tamoxifen, or any oestrogen-containing medicines such as hormone replacement therapy (HRT).

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  • Before you start this treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about anastrozole and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take one 1 mg tablet of anastrozole each day, exactly as your doctor tells you to. Your dose will be printed on the label of the tablet pack to remind you.

  • You may take anastrozole at whatever time of day you find easiest to remember, but try to take your doses at the same time each day. This will help you to avoid missing any doses.

  • You can take the tablet before or after a meal.

  • Se dimentichi di prendere una dose, prendila appena te ne ricordi. Se non te ne ricordi fino al giorno successivo, salta la dose dimenticata. Non prendere due dosi insieme per compensare una dose dimenticata.

  • Try to keep your regular appointments with your doctor or clinic. This is so your doctor can check on your progress. Anastrozole lowers the levels of female hormones in your body, which can reduce the strength of your bones. You will need to have bone density tests (before and during your treatment) to check for this.

  • Anastrozole is a long-term treatment so it's important to continue to take the tablets regularly unless your doctor tells you otherwise. It is likely you will need to take the tablets for five years.

  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking anastrozole.

  • Se acquisti dei medicinali, verifica con un farmacista che siano sicuri da assumere insieme agli altri tuoi medicinali.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with anastrozole. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common anastrozole side-effects

Cosa posso fare se sperimento questo?

Vampate di calore

Cerca di mantenerti fresco indossando abiti leggeri e ariosi

Sensazione di malessere (nausea) o vomito, perdita di appetito

Attieniti a pasti semplici - evita cibi ricchi o piccanti

Feeling weak or sleepy

This can happen when you first start treatment but quickly settles. Do not drive and do not use tools or machines if affected

Mal di testa

Bevi molta acqua e chiedi al tuo farmacista di consigliarti un antidolorifico adatto. Se i mal di testa persistono, informa il tuo medico

Diarrea

Bevi molta acqua per reintegrare i liquidi persi

Skin rash, joint aches and pains, vaginal dryness or bleeding, hair thinning, carpal tunnel syndrome, 'pins and needles', taste changes

Se uno di questi diventa problematico, parla con il tuo medico per un consiglio

Importante: There have been numerous reports of depression in women taking anastrozole. If you develop any segni della depressione whilst being treated with anastrozole, make an appointment to see your doctor.

Se si verificano altri sintomi che ritieni possano essere dovuti alle compresse, parla con il tuo medico o farmacista per ulteriori consigli.

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  • Conservare in un luogo fresco e asciutto, lontano da fonti di calore e luce diretta.

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Domande frequenti

What type of breast cancer does anastrozole treat?

Anastrozole is used for treating breast cancers that require the hormone oestrogen to grow. It works by reducing the amount of oestrogen in the body, which helps to slow the growth of these cancer cells.

How does anastrozole specifically reduce oestrogen levels in women who have been through menopause?

In women who have gone through menopause, oestrogen is mainly produced from other sex hormones called androgens. An enzyme called 'aromatase' is necessary for this conversion to happen. Anastrozole works by blocking (inhibiting) this aromatase enzyme, thereby reducing the amount of oestrogen in the body.

Can anastrozole be taken by women who have not yet gone through menopause?

No, anastrozole should not be taken by women who are still having menstrual periods, as it is only suitable for women who have already gone through the menopause.

Are there any specific medicines I should tell my doctor about before starting anastrozole, besides prescription drugs?

Yes, it is important to inform your doctor about all medicines you are taking, including any available without a prescription, as well as herbal remedies and complementary medicines. Specifically, you must tell your doctor if you are taking tamoxifen or any oestrogen-containing medicines, such as hormone replacement therapy (HRT).

How long will I need to take anastrozole?

Anastrozole is a long-term treatment, and you will likely need to take the tablets for five years consistently, unless your doctor advises otherwise.

What should I do if I forget to take a dose of anastrozole?

If you forget a dose, take it as soon as you remember. However, if you don't remember until the following day, you should skip the missed dose. Do not take two doses together to compensate for a forgotten dose.

What are the common side-effects of anastrozole and what can I do to manage them?

Common side-effects include hot flushes (try wearing light clothes), feeling sick or being sick (stick to simple meals), feeling weak or sleepy (this usually settles, but avoid driving or using machinery if affected), headache (drink water, ask a pharmacist for painkiller advice), and diarrhoea (drink plenty of water). Other side effects like skin rash, joint aches, vaginal dryness, hair thinning, carpal tunnel syndrome, 'pins and needles', and taste changes should be discussed with your doctor if they become bothersome.

What should I do if I notice changes in my mood, such as depression, while taking anastrozole?

There have been reports of depression in women taking anastrozole. If you develop any signs of depression during your treatment, you should make an appointment to see your doctor.

Ulteriori letture e riferimenti

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Storia dell'articolo

Le informazioni su questa pagina sono scritte e revisionate da clinici qualificati.

  • Prossima revisione prevista: 26 Nov 2026
  • 27 Nov 2023 | Ultima versione

    Ultimo aggiornamento di

    Michael Stewart, MRPharmS

    Revisione paritaria di

    Sid Dajani
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