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Can I take .metropolol and .losartan together?

Drug interaction guide

Taking metoprolol and losartan together can cause your blood pressure to drop lower than intended. This may make you feel dizzy, lightheaded, or faint, especially when standing up quickly. It can also slow your heart rate more than usual.

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Why this happens

Both medicines work to lower blood pressure but in different ways. Metoprolol is a beta-blocker that slows the heart and reduces its workload, while losartan is an angiotensin II receptor blocker (ARB) that relaxes blood vessels. When used together, their effects add up (an additive effect), which can lead to excessively low blood pressure (hypotension) or a very slow pulse (bradycardia).

You should use caution when taking these together, especially when starting the combination or increasing the dose. Monitor your blood pressure regularly at home if possible. To prevent dizziness, get up slowly from a sitting or lying position. If you feel very dizzy, faint, or notice a very slow heartbeat, contact your doctor. Do not stop taking either medicine without medical advice, as stopping metoprolol suddenly can cause heart problems.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
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