Can I take Eplerenone and Lansoprasole together?
Drug interaction guide
Originally published 14 Mar 2026
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There is no known significant interaction between eplerenone and lansoprazole. It is generally considered safe to take these two medications together.
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Why this happens
Eplerenone and lansoprazole are processed by different pathways in the body. Eplerenone is primarily broken down by a liver enzyme called CYP3A4, while lansoprazole is mainly handled by CYP2C19 and CYP3A4. Lansoprazole does not significantly interfere with the way eplerenone is absorbed, used, or removed from the body.
What you should do
Back to contentsYou can continue to take both medications as prescribed by your doctor. No special precautions or dose adjustments are usually necessary when using these two drugs together. Always inform your healthcare provider of all medications and supplements you are taking.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Treatment and medication
Can I take Bisoprolol and Ramipril together?
Taking these two medicines together can cause your blood pressure to drop lower than usual, especially when you first start the combination or when your dose is increased. This might make you feel dizzy, lightheaded, or faint. It can also occasionally lead to increased levels of potassium in your blood or affect how your kidneys work.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

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