Can I take Epipen adrenaline and Loratadine together?

Why this happens

Adrenaline works quickly to reverse life-threatening symptoms of anaphylaxis (like swelling and low blood pressure), while loratadine is a long-acting antihistamine that blocks histamine receptors to reduce milder symptoms like itching or hives. They work through different pathways in the body and do not interfere with each other's effectiveness or metabolism.

If you are experiencing a severe allergic reaction (anaphylaxis), use your EpiPen immediately as instructed and call emergency services (999). Do not rely on loratadine to treat a severe reaction, as it works too slowly. You can continue to take your prescribed loratadine for hay fever or hives as usual, even if you have had to use an EpiPen recently.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.