Can I take Empagliflozin and Mirtazapine together?
Drug interaction guide
Originally published 12 May 2026
Meets Patient’s editorial guidelines
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There is no direct interaction between empagliflozin and mirtazapine. However, both medications can occasionally cause a drop in blood pressure when you stand up (postural hypotension). Taking them together might slightly increase the risk of feeling dizzy or light-headed.
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Why this happens
Empagliflozin is a diuretic-like medicine that removes sugar and fluid via urine, which can lower blood volume. Mirtazapine can sometimes affect blood pressure regulation. Together, they may have an additive effect on lowering blood pressure.
What you should do
Back to contentsIt is generally safe to take these medicines together. To stay safe, stand up slowly from a sitting or lying position to avoid dizziness. Ensure you drink plenty of water to stay hydrated. If you feel very dizzy or faint, speak to your doctor or pharmacist.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
12 May 2026 | Originally published
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