Can I take Clopidogrel and Rovoststatin together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
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Taking these two medicines together can increase the amount of rosuvastatin in your blood. This may increase the risk of side effects, particularly muscle pain or weakness.
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Why this happens
Clopidogrel can interfere with a specific protein (OATP1B1) that helps your liver process rosuvastatin. When this protein is blocked, the level of rosuvastatin in your body rises.
What you should do
Back to contentsYou can take these together, but your doctor may need to adjust your rosuvastatin dose. If you are taking clopidogrel, the dose of rosuvastatin should usually not exceed 20mg per day. Tell your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
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