Can I take Amlodipine and Isosorbide mononitrate together?

Why this happens

Both medicines work by relaxing and widening your blood vessels (vasodilation) to lower blood pressure and treat chest pain. Because they both do this in different ways, their effects add together, which can lead to an exaggerated drop in blood pressure.

It is common for these to be prescribed together, but you should be careful. When starting this combination or increasing the dose, get up slowly from a sitting or lying position to avoid dizziness. If you feel very dizzy, sit or lie down until the feeling passes. Contact your doctor if you experience persistent dizziness, fainting, or a racing heartbeat.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.