Can I take Amitriptyline and Mycophenolate mofetil together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
There is no known direct interaction between amitriptyline and mycophenolate mofetil. However, both medications can occasionally cause side effects that affect your blood cell counts or digestive system.
In this article:
Video picks for Drug interactions
Continue reading below
Why this happens
These drugs work through completely different pathways in the body. Amitriptyline affects brain chemicals (neurotransmitters), while mycophenolate mofetil suppresses the immune system. They do not interfere with how the other is absorbed, broken down, or removed from the body.
What you should do
Back to contentsYou can safely take these two medicines together. As with any medication, you should monitor for side effects. If you notice unusual bruising, persistent sore throats, or severe stomach upset, contact your doctor, as these can be side effects of mycophenolate mofetil specifically.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions
Treatment and medication
Can I take 150 and Zigduo together?
Taking aspirin (75mg to 150mg) with Xigduo (which contains dapagliflozin and metformin) can increase the risk of your blood sugar dropping too low (hypoglycaemia). It may also increase the risk of a rare but serious condition called lactic acidosis, where too much acid builds up in your blood.
Treatment and medication
Can I take Empagliflozin and Mirtazapine together?
There is no direct interaction between empagliflozin and mirtazapine. However, both medications can occasionally cause a drop in blood pressure when you stand up (postural hypotension). Taking them together might slightly increase the risk of feeling dizzy or light-headed.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.
Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.