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Can I take 75 and Atorvastatin together?

Drug interaction guide

Taking aspirin and atorvastatin together can slightly increase the risk of muscle pain or weakness. It may also increase the risk of bruising or bleeding, particularly in the stomach. However, these two medicines are very commonly prescribed together because their combined benefit in preventing heart attacks and strokes usually outweighs these risks.

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Why this happens

Both medicines can affect the muscles, and aspirin's blood-thinning effect can be more pronounced when the liver is also processing a statin.

You can take these medicines together, but you should be alert for any unexplained muscle pain, tenderness, or weakness. You should also watch for signs of bleeding, such as dark, tarry stools or unusual bruising. It is best to avoid or strictly limit alcohol while taking these medications, as both can affect your liver and increase the risk of stomach irritation. Always follow the specific dosing instructions provided by your doctor.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
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