Can I take 50 and Gliclazide together?
Drug interaction guide
Originally published 12 May 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
Taking alcohol with gliclazide can cause your blood sugar levels to drop too low (hypoglycaemia). It can also occasionally cause an unpleasant reaction including flushing, feeling sick, and a fast heartbeat.
In this article:
Video picks for Drug interactions
Continue reading below
Why this happens
Alcohol stops the liver from releasing glucose into the bloodstream, which adds to the blood-sugar-lowering effect of gliclazide. Additionally, some people have a 'disulfiram-like' reaction where alcohol isn't broken down properly in the body.
What you should do
Back to contentsIt is best to avoid alcohol or keep your intake very low. Never drink on an empty stomach, as this increases the risk of a 'hypo'. Always carry a sugary snack with you and monitor your blood sugar more closely if you do choose to drink.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions
Drug interactions checker
Can I take Colecalciferol and Tizanidine together?
There are no known significant interactions between colecalciferol and tizanidine. It is generally considered safe to take these two medications together.
Drug interactions checker
Can I take Pregabalin and Prozac together?
Taking pregabalin and Prozac (fluoxetine) together can increase the risk of side effects that affect your brain and nervous system. You may feel more drowsy, dizzy, or confused. It can also make it harder to concentrate or perform tasks that require alertness. In some cases, especially in older adults, it may lead to impaired thinking or coordination. There is also a small but serious risk of a rare condition called serotonin syndrome, which can cause shivering, sweating, and a fast heartbeat.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
12 May 2026 | Originally published
Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.
Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.