Can I take 50 and Famotidine together?
Drug interaction guide
Originally published 14 Mar 2026
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Famotidine can significantly reduce the amount of 50 (dasatinib) that your body absorbs. This means the cancer medication may not work as well as it should to treat your condition.
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Why this happens
Dasatinib (50) needs a very acidic environment in the stomach to dissolve properly so it can be absorbed into your bloodstream. Famotidine is an H2 blocker that reduces stomach acid. By making the stomach less acidic, famotidine prevents the dasatinib from dissolving and entering your system.
What you should do
Back to contentsYou should not take famotidine while you are being treated with dasatinib. If you have symptoms of heartburn or acid reflux, speak to your doctor or specialist. They may suggest using an antacid (like Gaviscon or Rennie) instead, but these must be taken at least 2 hours before or 2 hours after your dasatinib dose.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

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