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Can I take 15 and Dapagliflozin together?

Drug interaction guide

Taking alcohol with dapagliflozin can increase the risk of a rare but serious condition called ketoacidosis (too much acid in the blood) and can also lead to low blood sugar (hypoglycaemia). Alcohol can also increase the risk of dehydration when taken with this medication.

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Why this happens

Dapagliflozin works by removing sugar through your urine, which changes how your body handles energy. Alcohol can interfere with the liver's ability to produce glucose and can lead to the buildup of ketones. Both substances also have a diuretic effect, meaning they make you lose more water.

It is best to avoid excessive alcohol consumption (binge drinking) while taking dapagliflozin. If you do choose to drink, do so in moderation and always have food with your drink. Be aware of the signs of ketoacidosis, such as nausea, stomach pain, excessive thirst, or confusion, and seek medical help immediately if these occur.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
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