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Can I take 10 and Tramadol together?

Drug interaction guide

Combining alcohol and tramadol can lead to dangerous levels of drowsiness, dizziness, and breathing difficulties. In severe cases, this combination can cause you to stop breathing or lead to a fatal overdose. Both substances also increase the risk of seizures (fits).

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Why this happens

Both alcohol and tramadol are 'central nervous system depressants'. This means they both slow down brain activity and the parts of the brain that control breathing. When taken together, their effects are added together, making the side effects much more powerful and dangerous.

You must not drink alcohol while taking tramadol. Even small amounts of alcohol can significantly increase the risk of life-threatening side effects. If you feel unusually sleepy, have shallow breathing, or feel faint, seek emergency medical help immediately.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
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