Can I take 10 and Sevodyne together?
Drug interaction guide
Originally published 14 Mar 2026
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Taking these two medicines together significantly increases your risk of severe bleeding, including internal bleeding and stomach ulcers. This is because both drugs thin the blood and affect how your body forms clots.
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Why this happens
Both medicines have 'antiplatelet' effects, meaning they stop blood cells (platelets) from sticking together. When used together, this effect is multiplied (synergistic), making it much harder for your blood to clot if you are injured or if you develop a small bleed in your stomach.
What you should do
Back to contentsDo not take these two medicines together unless specifically instructed and monitored by your doctor. If you are already taking them, contact your GP or pharmacist immediately. Seek urgent medical help if you notice signs of bleeding, such as dark 'tarry' stools, coughing up blood, or bruising that appears for no reason.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Taking paracetamol (acetaminophen) and trazodone together is generally considered safe, but there is a small risk of increased side effects. Both substances are processed by the liver, and in some cases, taking them together might slightly increase the levels of trazodone in your blood. This could make you feel more drowsy or dizzy than usual. Additionally, both medications can occasionally affect your liver function, so using them together over a long period requires caution.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
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