Can I take 1.5mg and Vitamin b12 together?
Drug interaction guide
Originally published 14 Mar 2026
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There is no known interaction between vitamin B12 and other medications or supplements based on the dosage provided (1.5mg). Vitamin B12 is a water-soluble vitamin that is generally very safe to take alongside other treatments.
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Why this happens
Vitamin B12 is absorbed in the small intestine and does not typically interfere with the chemical pathways, liver enzymes, or kidney excretion processes used by most other drugs. It does not have any known additive or opposing effects when taken with common medications.
What you should do
Back to contentsYou can safely take vitamin B12. If you are taking 1.5mg (1500 micrograms) as a supplement, this is a high dose compared to the daily requirement, so ensure this has been recommended by a healthcare professional to treat a specific deficiency. Always inform your doctor or pharmacist of all supplements you are taking.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Treatment and medication
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Taking these two medicines together can significantly increase the amount of desmopressin in your blood. This can lead to your body holding onto too much water, which can cause a dangerous drop in your blood salt levels (hyponatraemia). Symptoms to watch for include severe headache, nausea, vomiting, confusion, or feeling very drowsy.
Treatment and medication
Can I take Acetaminophen and Trazodone together?
Taking paracetamol (acetaminophen) and trazodone together is generally considered safe, but there is a small risk of increased side effects. Both substances are processed by the liver, and in some cases, taking them together might slightly increase the levels of trazodone in your blood. This could make you feel more drowsy or dizzy than usual. Additionally, both medications can occasionally affect your liver function, so using them together over a long period requires caution.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
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