
Gene discovery may explain why some people cope on little sleep
Revisione paritaria di Natalie HealeyUltimo aggiornamento di Ashwin BhandariUltimo aggiornamento 30 Ago 2019
Rispetta le linee guida editoriali
- ScaricaScarica
- Condividi
- Language
- Discussione
- Versione audio
- Add to preferred sources on Google
A gene which is linked to feeling fully rested after just a few hours of sleep has been identified by researchers.
Video picks for Sonno e insonnia
High-profile figures such as Donald Trump and Angela Merkel claim they require just four hours of sonno a day. Scientists may now have discovered why.
Experts at the University of California San Francisco had previously discovered a rare gene which promotes 'natural sleep', allowing individuals who sleep four hours a night to feel fully rested when waking up. A decade later, they have found a second gene which supports this evidence.
By observing a family with several members who need less sleep than average, the researchers identified another gene that they believe has a direct impact on how much someone sleeps.
People with the mutated ADRB1 gene, which has so far been found in more than 50 families, sleep for two hours less than the average person.
In 2009, Fu's team discovered that people who had inherited a particular mutation in a gene called DEC2 averaged only six and a half hours of sleep per night. Study participants lacking the mutation averaged eight hours.This finding was the first conclusive evidence that natural short sleep is, at least in some cases, genetic. Because this mutation is rare, however, it couldn't account for all of them.
"Before we identified the first short-sleep gene, people weren't thinking about sleep duration in genetic terms," said author Ying-Hui Fu. "Sleep can be difficult to study using the tools of human genetics because people use alarms, coffee and pills to alter their natural sleep cycles."
Fu led the research teams that discovered both short sleep genes, the newest of which is described in a paper published in the journal Neuron.
When scientists altered the ADRB1 gene in mice, they slept for 55 fewer minutes than regular mice - which suggests that this gene is related to not needing as much sleep.
Despite sleeping less, natural short sleepers don't suffer any of the adverse health effects associated with sleep deprivation.
"Today, most people are chronically sleep-deprived. If you need eight to nine hours, but only sleep seven, you're sleep-deprived," Fu said. "This has well-known, long-term health consequences. You're more likely to suffer from cardiovascular disease, cancer, dementia, metabolic problems and a weakened immune system."
Patient picks for Sonno e insonnia

Vita sana
How to fix your sleep schedule with a healthy bedtime routine
Un buon programma di sonno ti aiuta a ottenere la giusta quantità di riposo ogni notte e ti impedisce di accumulare un 'debito di sonno' che ti lascia non al meglio. Cosa rende un buon programma di sonno e come una routine di sonno salutare ti aiuta ad adottarne uno?
di Lawrence Higgins

Vita sana
How revenge bedtime procrastination affects your health - and how to avoid it
If you’ve ever stayed up late scrolling on your phone when you know you should be asleep, you’re not alone. You stay awake until the early hours to watch one more episode on Netflix, but when the morning rolls around, you’re exhausted. It’s something many of us do - and it’s called revenge bedtime procrastination.
di Lydia Smith
Continua a leggere sotto
About the authorView full bio

Ashwin Bhandari
Medical Writer
BA Journalism
About the reviewerView full bio

Natalie Healey
Freelance journalist
BSc (Hons) Biomedical Science
She is a London-based health journalist who has been writing about science and medicine for several years. She is the former head of editorial at Patient.
Storia dell'articolo
Le informazioni su questa pagina sono revisionate da clinici qualificati.
30 Ago 2019 | Ultima versione

Chiedi, condividi, connettiti.
Esplora le discussioni, fai domande e condividi esperienze su centinaia di argomenti di salute.

Non ti senti bene?
Valuta i tuoi sintomi online gratuitamente
Iscriviti alla newsletter di Patient
La tua dose settimanale di consigli sulla salute chiari e affidabili - scritti per aiutarti a sentirti informato, sicuro e in controllo.
By subscribing you accept our Informativa sulla Privacy. Puoi annullare l'iscrizione in qualsiasi momento. Non vendiamo mai i tuoi dati.