Join a study investigating a new multi-strain bacterial product for constipation

About this constipation treatment research study

The research focuses on understanding how a multi-strain bacterial product affects constipation symptoms, gut transit, and fermentation patterns in the digestive system.

By combining clinical assessments with symptom tracking, the study will provide insights into how the product interacts with the gut and whether it may be helpful for some individuals.

The study team is recruiting adults who have ongoing constipation and can attend clinic appointments in London.

Eligibility ensures that the results reflect the intended patient population and that participation is safe and appropriate.

If you think the study may be relevant to your symptoms, the full criteria on the study page can help you confirm.

You may be suitable if you:

• Experience chronic constipation.

• Are aged 18 to 70.

• Live in the UK.

• Can attend the London clinic.

If you join the study, you will follow a structured plan that includes clinic visits, taking the bacterial product, and completing symptom tracking.

These activities allow the research team to measure changes in gut function over the study period. All procedures are explained in advance and scheduled to minimise disruption to your daily routine.

Participation includes:

• Three in-person clinic visits.

• Taking the supplied bacterial product.

• Recording symptoms.

• Completing breath tests and gut transit assessments.

To understand how the product affects digestion, participants undertake a range of non-invasive tests. These help measure the movement of food through the gut, fermentation activity, and changes in bowel habits.

Each assessment is overseen by specialist clinicians who provide full guidance.

Assessments may include:

• Hydrogen and methane breath tests.

• Gut transit studies.

• Symptom scoring tools.

• Structured digestive health questionnaires.

Taking part offers the chance to support important research into microbiome-based treatments.

Although improvements cannot be guaranteed, many participants value the opportunity for structured clinical assessment and involvement in developing new approaches to constipation care.

Participants receive:

• Specialist assessments at no cost.

• Reimbursement of travel expenses.

• Compensation for time.

• Ongoing support throughout the study.

• Freedom to withdraw at any time.

Joining the constipation study

You can read the full details and express your interest by visiting the study page.

Apply to take part