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Mobility impairment and off legs in adults

Professionisti Medici

Professional Reference articles are designed for health professionals to use. They are written by UK doctors and based on research evidence, UK and European Guidelines. You may find one of our articoli sulla salute more useful.

Gait abnormalities or unsteadiness are a common presenting complaint, especially in older patients. It may be a trivial complaint with no underlying pathology or herald a more serious illness.

The concept of 'off legs' usually refers to elderly patients, who were previously mobile and active, with a sudden deterioration. The cause of 'off legs' is usually an acute illness - eg, chest infection, urinary tract infection. 'Off legs' is a non-specific presentation, with a wide variety of causes. In emergency departments, it is a high-risk presentation, with a 30-day mortality rate of 6%.1

Those who lose independent mobility are less likely to remain in the community, have higher rates of disease, have a poorer quality of life and a greater likelihood of social isolation.

This article is primarily focused on mobility impairment in adults.

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How common is mobility impairment in adults? (Epidemiology)

  • The most common risk factors for mobility impairment are older age, low physical activity, obesity, strength or balance impairment, and chronic diseases such as diabete oppure artrite.

  • The prevalence of gait and balance disorders is around 10 % between the ages of 60 and 69 years and more than 60% in those over 80 years.2

  • About 30% of people aged 65 years and over have a fall at least once each year, increasing to 50% in people aged 80 years and over.3

  • In 2016-2017 there were around 210,553 falls-related emergency hospital admissions among people aged 65 years and over, with around 67% of these people aged 80 years and over.

Storia

  • Patients may complain directly of problems with walking or simply of unsteadiness.

  • It is important to clarify exactly what the patient feels - eg, which aspect of walking is difficult.

  • Ask about falls - establish when the last fall occurred, how frequent falls are and whether there are any syncope or presyncope symptoms. See the separate Prevention of Falls in the Elderly article for details.

  • Also, determine duration of problems.

  • A full review of systems is required, especially looking for cardiac or neurological disease.

  • Ask specifically for features suggestive of cord compression - eg, urinary retention, sensory and/or motor loss.

  • Take a full drug history, especially as the aetiology may relate to polypharmacy or drug side-effects.

Esame

  • Pulse rate, rhythm, volume and presence or absence of carotid bruits.

  • Blood pressure including postural hypotension.

  • Cardiovascular examination looking particularly for murmurs - eg, stenosi aortica.

  • Full neurological examination looking for pyramidal, extrapyramidal and cerebellar dysfunction, and testing sensation for signs of peripheral neuropathy. See also the separate Esame neurologico degli arti inferiori articolo.

  • Do not forget the possibility of fractures and injuries - look for leg asymmetry and test the spine and lower limbs for tenderness.

  • Examine the gait - asymmetrical or symmetrical problems, presence of waddling gait, broad-based gait, scissoring gait (bilateral leg spasticity), or ataxia.

  • Consider further testing:3

    • With the 'Timed Up & Go' test, you time the person getting up from a chair without using their arms, walking three metres, turning around, returning to the chair, and sitting down. If the person usually uses a walking aid, this can be used during the test.

    • A score of 12-15 seconds or more has been shown to indicate high risk of falls in older people.

    • Also consider the 'Turn 180°' test where you ask the person to stand up and step around until they are facing the opposite direction. If the person takes more than four steps, further assessment should be considered.

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Causes of mobility impairment

Causes of difficulty in walking can be broad and the following table lists some of these:

Cause

Examples of diseases

Vascolare

Cardiaco

Arrhythmias.

Ipotensione.

Ipotensione posturale.

Neurologico

Transient ischaemic attacks.

Cerebrovascular accident.

Multi-infarct dementia.

Neurologico

Pyramidal disease

Sclerosi multipla.

Cord compression.

Motor neurone disease.

Siringomielia.

Tumori del midollo spinale.

B12 deficiency.

Sifilide.

Extrapyramidal disease

Discinesia tardiva.

Akathisia.

morbo di Parkinson.

Parkinsonism - eg, drug-induced.

Malattia cerebellare

Cerebellar tumours.

Any ataxia - eg, Atassia di Friedreich.

Encefalopatia di Wernicke.

Altro

Neuropatia periferica.

Chorea.

Ortopedia

Painless

Arthrodesis of hip joints.

Painful

Arthritides - eg, osteoartrite, l'artrite reumatoide.

Spinal disease - eg, stenosis.

Fractures (remember elderly patients may not be able to communicate that they are in pain).

Problemi ai piedi - eg, corns,4 bunions, ill-fitting shoes.

Balance and co-ordination

Alzheimer's dementia.

Labyrinthitis.

Degenerative changes in the inner ear.

Muscoli

Myopathies.

Metabolico

Diabetes mellitus - eg, autonomic neuropathy or foot drop.

Disturbi della tiroide.

Altri

Toxins/drugs

Anti-hypertensive medication.

Sedatives.

Antipsychotics.

Ethanol.

Anticonvulsants.

Psicologico

Loss of confidence, including depression.

Causes of 'off legs'

As mentioned above, 'off legs' usually present in elderly patients and can be interpreted in various ways. This ranges from unsteadiness and difficulty with walking to capogiro or lethargy. The exact meaning should be sought during the assessment of the patient.

The causes of 'off legs' are usually acute and some causes include:

  • Urina oppure infezioni toraciche.

  • Disidratazione.

  • Neurological causes - eg, head injury, cord compression/cauda equina syndrome.

  • Orthopaedic causes - eg, fractures (consider especially in elderly patients with osteoporosi who can fracture their neck of femur without major trauma).

  • Metabolic abnormalities - eg, iponatriemia, ipercalcemia, ipoglicemia or hyperglycaemia.

  • Alcohol, drug or medications, especially as there are risks of polypharmacy in elderly patients.

  • Ipossia.

These should be guided by the history and examination and may include cerebral imaging (eg, CT or MRI scanning) and blood tests (eg, TFTs, sifilide serology, etc).

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This is directed towards the underlying cause. If the cause is multifactorial then a multidisciplinary approach may be appropriate - eg, physiotherapist, occupational therapists and allied healthcare professionals.

See the separate Prevention of Falls in the Elderly articolo.

Ulteriori letture e riferimenti

  1. Nemec M, Koller MT, Nickel CH, et al; Patients presenting to the emergency department with non-specific complaints: the Basel Non-specific Complaints (BANC) study. Acad Emerg Med. 2010 Mar;17(3):284-92. doi: 10.1111/j.1553-2712.2009.00658.x.
  2. Pirker W, Katzenschlager R; Gait disorders in adults and the elderly : A clinical guide. Wien Klin Wochenschr. 2017 Feb;129(3-4):81-95. doi: 10.1007/s00508-016-1096-4. Epub 2016 Oct 21.
  3. Cadute - valutazione del rischio; NICE CKS, gennaio 2019 (accesso solo UK)
  4. Al Aboud AM, Badri T; Corns. StatPearls Publishing; 2019-. 2019 Mar 2.

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